CENPJ (Vector pUC, Accession No. BC113662)

Length: 4017 Sequence: atgttcctga tgccaacctc ttcagagtta aacagtgggc agaacttcct aacccagtgg atgaccaatc cttctcgggc tggggtcata ttaaatcgtg gatttcctat tttggaagca gacaaagaga agcgagcagc tgtggacatt tctaccagct ttcctattaa aggcacacat ttttctgata gcttcagctt tataaatgaa gaagattcac ttcttgaaga acagaagttg gagtcaaaca acccttacaa accacagtca gataaatctg aaacccatac agcctttcct tgcattaaaa agggaccaca ggtagcggca tgtcacagtg ctcctggaca ccaggaagaa aacaaaaatg acttcatccc agatcttgcg agtgaattca aagaaggggc ttataaagac ccacttttta aaaaacttga acagctgaaa gaagtacaac agaagaagca ggaacaattg aagaggcaac agttggagca actacagaga ctcatggaag aacaagagaa gctgctcacc atggtgtctg ggcagtgcac acttccaggt ttgagtttac tgcctgatga tcagagccag aagcacaggt ctccaggaaa taccaccact ggagagagag ccacatgctg cttcccatca tatgtctacc cggacccaac ccaggaagaa acatacccgt ccaacatttt atcccatgag caaagcaact tctgtagaac tgctcatgga gattttgtct taacttcaaa acgtgcgtct cctaatttat tttctgaggc acagtatcaa gaagcacctg tggaaaaaaa taatttaaaa gaagaaaacc gtaaccatcc tacaggagaa agtatcttat gttgggagaa agtgacagaa cagattcagg aagcaaatga taagaactta caaaaacatg atgattcctc agaagtggct aatattgaag aaaggcccat taaagctgct attggagaaa ggaaacagac ctttgaagat tacttagaag aacaaattca gttggaagag caagaactga agcaaaaaca gctgaaggaa gcagaaggac cattgccaat caaagcaaaa ccaaaacaac catttttaaa acgaggagaa ggtttagcta gatttactaa tgccaaatct aagtttcaaa aaggcaaaga aagtaaacta gtgactaacc agagcacttc cgaggaccag ccgctgttta aaatggatag acagcaactc cagcggaaaa ccgctcttaa aaataaagag ctgtgtgcag acaaccctat ccttaaaaag gacagtaaag ctagaaccaa gagtggttct gtcaccctca gtcagaagcc gaaaatgctg aagtgtagta acaggaaaag tctttctccg tcaggattga aaatacagac ggggaagaaa tgtgatgggc agtttagaga ccagatcaaa tttgaaaaca aagtcacatc taataataaa gaaaatgtaa ctgagtgtcc aaaaccttgc gatactggct gcacagggtg gaataagaca caaggtaaag acagacttcc tctttcaaca gggccggcca gccggctggc tgctaagagc cccataaggg agaccatgaa agagtctgaa tcttctcttg acgtttctct tcagaaaaag ttagagactt gggaacgaga aaaggaaaag gaaaatttgg aattagatga atttttgttt ttagaacaag ctgctgatga aatatcattt tctagtaatt cctcatttgt actgaaaatc ttagaaaggg atcaacagat ctgcaaaggt caccggatgt cttccacccc tgtcaaagct gtgccacaga agacaaatcc ggcagatccc attagtcatt gtaaccgcag tgaggatttg gaccacactg cacgtgagaa ggagagtgag tgtgaagtcg cacccaaaca acttcattca ttgtcctcag ctgatgaatt gagggaacag ccttgtaaaa tcaggaaagc cgtccaaaag agcacttctg aaaatcagac tgaatggaat gcacgtgacg atgaaggtgt tccaaatagt gacagtagca ctgactctga ggaacagctt gatgttacca taaaaccatc gactgaggat agagagaggg gcatcagcag cagagaggat agcccacaag tctgtgatga taaggggcct tttaaggaca ccaggaccca agaagataaa aggagagatg ttgatctgga tttgtctgat aaagattaca gtagcgatga gtctatcatg gaaagcataa aacataaagt gtctgagccc tcgagatcct catccctaag tctgagtaaa atggactttg atgatgaaag aacttggact gaccttgaag agaatttgtg taaccatgat gttgttcttg ggaatgaatc cacttatggg acgccgcaga catgctaccc taataatgaa ataggtatcc tggacaaaac aataaaaagg aagattgcac cagtcaagag gggagaagac ttgagcaagt ccaggaggag cagaagtcct cctacatcgg agctgatgat gaaattcttt ccttctttga aaccaaaacc aaagtcagat tcacacttgg gaaatgaact caagttaaac ataagtcaag accaaccacc tggtgacaat gctcgatccc aggttttgag agagaaaatt attgaattgg aaacagaaat agaaaagttt aaagctgaga acgcatcttt agctaaactt cgcattgaac gagaaagtgc cttggaaaaa ctcaggaaag aaattgcaga cttcgaacaa cagaaagcaa aagaattagc tcgaatagaa gagtttaaaa aggaggagat gaggaagcta caaaaggaac gtaaagtttt tgaaaagtat actacagctg caagaacttt tccagataaa aaggaacgtg aagaaataca gactttaaaa cagcaaatag cagatttacg ggaagatttg aaaagaaagg agaccaaatg gtcaagtaca cacagccgtc tcagaagcca gatacaaatg ttagtcagag agaacacaga cctccgggaa gaaataaaag tgatggaaag attccgactg gatgcctgga agagagcaga agccatagag agcagcctcg aggtggagaa gaaggacaag cttgcgaaca catctgttcg atttcaaaac agtcagattt cttcaggaac ccaggtagaa aaatacaaga aaaattatct tccaatgcaa ggcaatccac ctcgaagatc caagtctgca cctcctcgtg atttaggcaa tttggataag ggacaagctg cctctcccag ggagccactt gaaccactga acttcccaga tcctgaatat aaagaggagg aggaagacca agacatacag ggagaaatca gtcatcctga tggaaaggtg gaaaaggttt ataagaatgg gtgccgtgtt atactgtttc ccaatggaac tcgaaaggaa gtgagtgcag atgggaagac catcactgtc actttcttta atggtgacgt gaagcaggtc atgccagacc aaagagtgat ctactactat gcagctgccc agaccactca cacgacatac ccggagggac tggaagtctt acatttctca agtggacaaa tagaaaaaca ttacccagat ggaagaaaag aaatcacgtt tcctgaccag actgttaaaa acttatttcc tgatggacaa gaagaaagca ttttcccaga tggtacaatt gtcagagtac aacgtgatgg caacaaactc atagagttta ataatggcca aagagaacta catactgccc agttcaagag acgggaatac ccagatggca ctgttaaaac cgtatatgca aacggtcatc aagaaacgaa gtacagatcc ggtcggataa gagttaagga caaggagggt aatgtgctaa tggacacgga Protein function: Plays an important role in cell division and centrosome function by participating in centriole duplication (PubMed:17681131, PubMed:20531387). Inhibits microtubule nucleation from the centrosome. Involved in the regulation of slow processive growth of centriolar microtubules. Acts as microtubule plus-end tracking protein that stabilizes centriolar microtubules and inhibits microtubule polymerization and extension from the distal ends of centrioles (PubMed:15047868, PubMed:27219064, PubMed:27306797). Required for centriole elongation and for STIL-mediated centriole amplification (PubMed:22020124). Required for the recruitment of CEP295 to the proximal end of new-born centrioles at the centriolar microtubule wall during early S phase in a PLK4-dependent manner (PubMed:27185865). May be involved in the control of centriolar-microtubule growth by acting as a regulator of tubulin release (PubMed:27306797). [The UniProt Consortium]