CCDC109B (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pU

Length: 747 Sequence: atgttgtcaa cagttggttc attccttcag gacctacaaa atgaagataa gggtatcaaa actgcagcca tcttcacagc agatggcaac atgatttcag cttctacctt gatggatatt ttgctaatga atgattttaa acttgtcatt aataaaatag catatgatgt gcagtgtcca aagagagaaa aaccaagtaa tgagcacact gctgagatgg aacacatgaa atccttggtt cacagactat ttacaatctt gcatttagaa gagtctcaga aaaagagaga gcaccattta ctggagaaaa ttgaccacct gaaggaacag ctgcagcccc ttgaacaggt gaaagctgga atagaagctc attcggaagc caaaaccagt ggactcctgt gggctggatt ggcactgctg tccattcagg gtggggcact ggcctggctc acgtggtggg tgtactcctg ggatatcatg gagccagtta catacttcat cacatttgca aattctatgg tcttttttgc atactttata gtcactcgac aggattatac ttactcagct gttaagagta ggcaatttct tcagttcttc cacaagaaat caaagcaaca gcactttgat gtgcagcaat acaacaagtt aaaagaagac cttgctaagg ctaaagaatc cctgaaacag gcgcgtcatt ctctctgttt gcaaatgcaa gtagaagaac tcaatgaaaa Protein function: Negatively regulates the activity of MCU, the mitochondrial inner membrane calcium uniporter, and thereby modulates calcium uptake into the mitochondrion. Does not form functional calcium channels by itself. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways. [The UniProt Consortium]