C7orf59 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC

Length: 300 Sequence: atgacttctg cactgaccca ggggctggag cgaatcccag accagctcgg ctacctggta ctgagtgaag gtgcagtgct ggcgtcatct ggggacctgg agaatgatga gcaggcagcc agtgccatct ctgagctggt cagcacagcc tgcggtttcc ggctgcaccg cggcatgaat gtgcccttca agcgcctgtc tgtggtcttt ggagaacaca cactgctggt gacggtgtca ggacagaggg tgtttgtggt gaagaggcag aaccgaggtc gggagcccat Protein function: As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V- ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. [The UniProt Consortium]