C6orf106 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pU

Length: 897 Sequence: atggagggca tggacgtaga cctggacccg gagctgatgc agaagttcag ctgcctgggc accaccgaca aggacgtgct catctccgag ttccagaggc tgctcggctt ccagctcaat cctgccggtt gcgccttctt cctggacatg accaactgga acctacaagc agcaattggc gcctattatg actttgagag cccaaacatc agtgtgccct ctatgtcctt tgttgaagat gtcaccatag gagaagggga gtcaatacct ccggatactc agtttgtaaa aacatggcgg atccagaatt ctggggcaga ggcctggcct ccaggggttt gtcttaaata tgtcggggga gaccaatttg gacatgtgaa catggtgatg gtgagatcgc tagagcccca agagattgca gatgtcagcg tccagatgtg cagccccagc agagcaggaa tgtatcaggg acagtggcgg atgtgcactg ctacaggact ctactatgga gatgtcatct gggtgattct cagtgtggag gtgggtggac ttttaggagt aacgcagcag ctgtcatctt ttgaaacgga gttcaacaca cagccgcatc gtaaggtaga aggaaacttc aacccttttg cctctcccca aaagaaccga caatcagatg aaaacaactt aaaagaccct gggggctccg agttcgactc gatcagcaaa aacacatggg ctcctgctcc tgacacatgg gctcctgctc ctgaccaaac tgagcaagac cagaatagac tgtcacagaa ctctgtaaat ctgtctccca gcagtcacgc aaacaactta tcagtagtga cttacagtaa ggggctccat gggccttacc ccttcggcca Protein function: Negative regulator of innate antiviral response. Blocks IRF3- dependent cytokine production such as IFNA, IFNB and TNF (PubMed:29802199). Interacts with IRF3 and inhibits IRF3 recruitment to type I IFN promoter sequences while also reducing nuclear levels of the coactivators EP300 and CREBBP (PubMed:29802199). [The UniProt Consortium]