BVES (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC, A

Length: 870 Sequence: atgttaactc taggatgtac cctttatatc gtctgggcca ctctctaccg atgtgccttg gatataatga tctggaactc tgtgttcttg ggtgtcaaca ttttgcatct gtcgtatctt ttatacaaga agagaccggt aaagattgaa aaggaactca gtggcatgta ccggcgattg tttgaaccac tccgtgtgcc tccagatttg ttcagaagac taactggaca gttttgcatg atccaaacct tgaaaaaggg ccaaacttat gctgcagagg ataaaacctc agttgatgac cgtctgagta ttctcttgaa gggaaaaatg aaggtctcct atcgaggaca ttttctgcat aacatttacc cctgtgcctt tatagattct cctgaattta gatcaactca gatgcacaaa ggtgaaaaat tccaggtcac cattattgca gatgataact gcagattttt atgctggtca agagaaagat taacatactt tctggaatca gaacctttct tgtatgaaat ctttaggtat cttattggaa aagacatcac aaataagctc tactcattga atgatcccac cttaaatgat aaaaaagcca aaaagctgga acatcagctc agcctctgca cacagatctc catgttggaa atgaggaaca gtatagccag ctccagtgac agtgacgacg gcttgcacca gtttcttcgg ggtacctcca gcatgtcctc tcttcatgtg tcatccccac accagcgagc ctctgccaag atgaaaccga tagaagaagg agcagaagat ggtgatgacg tttttgaacc ggcatctcca aatacattga aagtccatca Protein function: Cell adhesion molecule involved in the establishment and/or maintenance of cell integrity. Involved in the formation and regulation of the tight junction (TJ) paracellular permeability barrier in epithelial cells (PubMed:16188940). Plays a role in VAMP3-mediated vesicular transport and recycling of different receptor molecules through its interaction with VAMP3. Plays a role in the regulation of cell shape and movement by modulating the Rho-family GTPase activity through its interaction with ARHGEF25/GEFT. Induces primordial adhesive contact and aggregation of epithelial cells in a Ca(2+)-independent manner. Also involved in striated muscle regeneration and repair and in the regulation of cell spreading. Important for the maintenance of cardiac function. Plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding and, probably, by increasing cell surface expression of the potassium channel KCNK2 and enhancing current density (PubMed:26642364). Is also a caveolae-associated protein important for the preservation of caveolae structural and functional integrity as well as for heart protection against ischemia injury. [The UniProt Consortium]