BVES (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC, A

Length: 1083 Sequence: atgaattata cagagtccag cccattgaga gaatcaactg ccataggttt tacacctgag ttagaaagta tcatacctgt gccttccaat aagaccactt gtgaaaactg gagagagata catcatctgg tttttcatgt agcaaatatt tgttttgcag ttgggttggt tattccaact actcttcacc ttcatatgat atttcttagg ggaatgttaa ctctaggatg taccctttat atcgtctggg ccactctcta ccgatgtgcc ttggatataa tgatctggaa ctctgtgttc ttgggtgtca acattttgca tctgtcgtat cttttataca agaagagacc ggtaaagatt gaaaaggaac tcagtggcat gtaccggcga ttgtttgaac cactccgtgt gcctccagat ttgttcagaa gactaactgg acagttttgc atgatccaaa ccttgaaaaa gggccaaact tatgctgcag aggataaaac ctcagttgat gaccgtctga gtattctctt gaagggaaaa atgaaggtct cctatcgagg acattttctg cataacattt acccctgtgc ctttatagat tctcctgaat ttagatcaac tcagatgcac aaaggtgaaa aattccaggt caccattatt gcagatgata actgcagatt tttatgctgg tcaagagaaa gattaacata ctttctggaa tcagaacctt tcttgtatga aatctttagg tatcttattg gaaaagacat cacaaataag ctctactcat tgaatgatcc caccttaaat gataaaaaag ccaaaaagct ggaacatcag ctcagcctct gcacacagat ctccatgttg gaaatgagga acagtatagc cagctccagt gacagtgacg acggcttgca ccagtttctt cggggtacct ccagcatgtc ctctcttcat gtgtcatccc cacaccagcg agcctctgcc aagatgaaac cgatagaaga aggagcagaa gatgatgatg acgtttttga accggcatct ccaaatacat tgaaagtcca tcagctgcct Protein function: Cell adhesion molecule involved in the establishment and/or maintenance of cell integrity. Involved in the formation and regulation of the tight junction (TJ) paracellular permeability barrier in epithelial cells (PubMed:16188940). Plays a role in VAMP3-mediated vesicular transport and recycling of different receptor molecules through its interaction with VAMP3. Plays a role in the regulation of cell shape and movement by modulating the Rho-family GTPase activity through its interaction with ARHGEF25/GEFT. Induces primordial adhesive contact and aggregation of epithelial cells in a Ca(2+)-independent manner. Also involved in striated muscle regeneration and repair and in the regulation of cell spreading. Important for the maintenance of cardiac function. Plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding and, probably, by increasing cell surface expression of the potassium channel KCNK2 and enhancing current density (PubMed:26642364). Is also a caveolae-associated protein important for the preservation of caveolae structural and functional integrity as well as for heart protection against ischemia injury. [The UniProt Consortium]