BAAT (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC, A

Length: 1257 Sequence: atgatccagt tgacagctac ccctgtgagt gcacttgttg atgagccagt gcatatccaa gctacaggcc tgattccctt tcagatggtg agttttcagg catcactgga agatgaaaac ggagacatgt tttattctca agcccactat agggccaatg aattcggtga ggtggacctg aatcatgctt cttcacttgg aggggattat atgggagtcc accccatggg tctcttctgg tctctgaaac ctgaaaagct attaacaaga ctgttgaaaa gagatgtgat gaataggcct ttccaggtcc aagtaaaact ttatgactta gagttaatag tgaacaataa agttgccagt gctccaaagg ccagcctgac tttggagagg tggtatgtgg cacctggtgt cacacgaatt aaggttcgag aaggccgcct tcgaggagct ctctttctcc ctccaggaga gggtctcttc ccaggggtaa ttgatttgtt tggtggtttg ggtgggctgc ttgaatttcg ggccagcctc ctagccagtc gtggcttcgc ctccttggcc ttggcttacc ataactatga agacctgccc cgcaaaccag aagtaacaga tttggaatat tttgaggagg ctgccaactt tctcctgaga catccaaagg tctttggctc aggcgttggg gtagtctctg tatgtcaagg agtacagatt ggactatcta tggctattta cctaaagcaa gtcacagcca cggtacttat taatgggacc aactttcctt ttggcattcc acaggtatat catggtcaga tccatcagcc ccttccccat tctgcacaat taatatccac caatgccttg gggttactag agctctatcg cacttttgag acaactcaag ttggggccag tcaatatttg tttcctattg aagaggccca ggggcaattc ctcttcattg taggagaagg tgataagact atcaacagca aagcacacgc tgaacaagcc ataggacagc tgaagagaca tgggaagaac aactggaccc tgctatctta ccctggggca ggccacctga tagaacctcc ctattctcct ctgtgctgtg cctcaacgac ccacgatttg aggttacact ggggaggaga ggtgatccca cacgcagctg cacaggaaca tgcttggaag gagatccaga gatttctcag gaagcacctc attccagatg tgaccagtca Protein function: Catalyzes the amidation of bile acids (BAs) with the amino acids taurine and glycine (PubMed:12810727, PubMed:8034703, PubMed:2037576, PubMed:12239217). More than 95% of the BAs are N-acyl amidates with glycine and taurine (PubMed:8034703). Amidation of BAs in the liver with glycine or taurine prior to their excretion into bile is an important biochemical event in bile acid metabolism (PubMed:12810727). This conjugation (or amidation) plays several important biological roles in that it promotes the secretion of BAs and cholesterol into bile and increases the detergent properties of BAs in the intestine, which facilitates lipid and vitamin absorption (PubMed:12810727). May also act as an acyl-CoA thioesterase that regulates intracellular levels of free fatty acids (PubMed:12810727, PubMed:8034703, PubMed:12239217). In vitro, catalyzes the hydrolysis of long- and very long-chain saturated acyl-CoAs to the free fatty acid and coenzyme A (CoASH), and conjugates glycine to these acyl-CoAs (PubMed:12810727). [The UniProt Consortium]