ATP6V1G1 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pU

Length: 357 Sequence: atggctagtc agtctcaggg gattcagcag ctgctgcagg ccgagaagcg ggcagccgag aaggtgtccg aggcccgcaa aagaaagaac cggaggctga agcaggccaa agaagaagct caggctgaaa ttgaacagta ccgcctgcag agggagaaag aattcaaggc caaggaagct gcggcattgg gatcccgtgg cagttgcagc actgaagtgg agaaggagac ccaggagaag atgaccatcc tccagacata cttccggcag aacagggatg aagtcttgga caacctcttg gcttttgtct gtgacattcg gccagaaatc catgaaaact accgcataaa Protein function: Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (PubMed:28296633). [The UniProt Consortium]