ASPM (Vector pUC, Accession No. BC034607)

Length: 3429 Sequence: atgtctctca gagcttatac tgctcggtgt aggttaaaca gactacgtcg tgcagcatgc cgtttgttta cttctgaaaa aatggttaaa gctattaaaa agcttgaaat tgaaattgaa gctaggcggt taattgttcg aaaagataga cacctatgga aagatgtggg agaacgtcag aaagtcctga attggctgtt gtcctacaat cctttgtggc ttcgaattgg tctagagaca acttatggag aactcatatc tttggaagat aacagtgatg tcacagggtt ggctatgttt attctgaatc gcctactttg gaatcctgat atagcagctg agtatagaca ccccactgtt cctcacctgt atagagatgg tcatgaagaa gctttgtcca agtttacatt gaaaaagtta ttgttgttgg tctgttttct tgattatgct aaaatttcca gactcattga tcatgatcct tgtctcttct gtaaagatgc cgaattcaag gctagtaaag aaatcctttt ggctttttca cgagatttcc taagtggtga aggtgacctt tcccgtcacc ttggcttatt gggattacct gttaaccatg ttcagacacc atttgatgaa tttgattttg ccgttacaaa tcttgccgta gacttgcaat gtggagtgcg ccttgtgcga accatggaac ttctcacaca gaactgggac ctctcaaaga aactcaggat tccggcaata agtcgtcttc aaaagatgca caatgttgac attgttcttc aagttcttaa atcacgagga attgaattaa gtgatgagca tggaaataca attctatcta aggatattgt ggataggcac agagaaaaaa ctctcaggtt gctttggaaa atagcgtttg cttttcaggt ggatatttcc cttaacttag atcaattaaa ggaagaaatt gcctttctaa aacacacaaa gagtataaag aaaacaatat ctctactatc atgccatttt gatgatctta ttaataagaa aaaaggcaaa agggatagtg gttcctttga acaatatagt gaaaacataa agttattgat ggattgggta aatgctgttt gtgccttcta taataaaaag gtggagaatt ttacagtgtc tttctcagac ggccgtgtgt tatgttacct gatccaccat taccatcctt gctatgtgcc atttgacgct atatgtcagc gtactactca aactgtggaa tgtacgcaaa ctggttcagt ggtattaaat tcatcatctg aatctgatga cagttctctg gatatgtctc ttaaagcatt tgatcatgaa aatacttcag agctatacaa agagctccta gaaaatgaaa agaaaaattt tcacttggtt aggtctgcag ttagagacct tggtggaata cctgctatga ttaatcattc agatatgtca aatacaattc cagatgaaaa ggtggttatt acctatttgt catttctttg tgcaaggctt ttggatcttc gtaaagaaat aagagctgct cgactcatac aaacaacatg gagaaaatat aaactaaaaa cagatctcaa acgccatcag gagagagaga aagctgcaag aattattcaa ttggctgtaa tcaattttct agcaaaacaa agattgagaa aaagagttaa tgcagcactc gtcattcaga aatattggcg aagagtctta gcacagagaa aattattaat gttaaaaaag gaaaagctgg aaaaagttca aaataaagca gcatcactta ttcaggctat gtggaggaga tatagagcca agaaatattt atgtaaagtg aaagctgcct gcaagattca agcctggtat agatgttgga gagcacacaa agaatatcta gctatattaa aagctgttaa aattattcaa ggttgcttct ataccaaact agagagaaca cggtttttga atgtgagagc atcagcaatt atcattcaga gaaaatggag agctatactt cctgcaaaga tagctcatga acacttctta atgataaaaa gacatcgagc tgcttgtttg atccaagcac attatagagg atataaagga aggcaggtct ttcttcggca gaaatctgct gctttgatca tacaaaaata tatacgagcc agggaggctg gaaagcatga aaggataaaa tatattgaat ttaaaaaatc tacagttatc ctacaagcac tggtgcgtgg ttggctagta cgaaaaagat ttttagaaca gagagccaaa attcgacttc ttcacttcac tgcagctgca tattatcacc tgaatgctgt tagaattcaa agagcctata aactttacct ggctgtgaag aatgctaaca agcaggttaa ttcagtcatc tgtattcaga gatggtttcg agcaagatta caagaaaaga gatttattca gaaatatcat agcatcaaaa agattgagca tgaaggtcaa gaatgtctga gccagcgaaa tagggctgca tcagtaatac agaaagcagt gcgccatttt ctcctccgta aaaagcagga aaaattcact agtggaatca ttaaaattca ggcattatgg agaggctatt cttggaggaa gaaaaatgat tgtacaaaaa ttaaagctat acgactaagt cttcaagttg ttaataggga gattcgagaa gaaaacaaac tctacaaaag aactgcactt gcacttcatt accttttgac atataagcac ctttctgcca ttcttgaggc cttaaaacac ctagaggtag ttactagatt gtctccactt tgttgtgaga acatggccca gagtggagca atttctaaaa tatttgtttt gatccgaagt tgtaatcgca gtattccttg tatggaagtc atcagatatg ctgtgcaagt cttgcttaat gtatctaagt atgagaaaac tacttcagca gtttatgatg tagaaaattg tatagatata ctattggagc ttttgcagat ataccgagaa aagcctggta ataaagttgc agacaaaggc ggaagcattt ttacaaaaac ttgttgtttg ttggctattt tactgaagac aacaaataga gcctctgatg tacgaagtag gtccaaagtt gttgaccgta tttacagtct ctacaaactt acagctcata aacataaaat gaatactgaa agaatacttt acaagcaaaa gaagaattct tctataagca ttccttttat cccagaaaca cctgtaagga ccagaatagt ttcaagactt aagccagatt gggttttgag aagagataac atggaagaaa tcacaaatcc cctgcaagct attcaaatgg tgatggatac gcttggcatt Protein function: Involved in mitotic spindle regulation and coordination of mitotic processes. The function in regulating microtubule dynamics at spindle poles including spindle orientation, astral microtubule density and poleward microtubule flux seems to depend on the association with the katanin complex formed by KATNA1 and KATNB1. Enhances the microtubule lattice severing activity of KATNA1 by recruiting the katanin complex to microtubules. Can block microtubule minus-end growth and reversely this function can be enhanced by the katanin complex (PubMed:28436967). May have a preferential role in regulating neurogenesis. [The UniProt Consortium]