AP4B1 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 2220 Sequence: atgccgtacc ttggctccga ggacgtggtg aaggagctga agaaggctct gtgcaatcct cacattcaag ctgataggct gcgctaccgg aatgtcatcc agcgagtgat taggtacatg actcaaggct tggacatgtc tggtgttttt atggaaatgg tgaaggccag tgccactgta gatattgtcc agaagaagtt ggtttatctg tacatgtgca catatgctcc cctgaaacca gatctggctc tcctggccat caatacgctg tgcaaagact gctcagaccc caatccaatg gtgcgagggc tggcgttacg gagcatgtgt agcctcagga tgcctggtgt gcaggagtat atacaacagc ctattctcaa tggtctgcgg gataaggctt catatgtcag gagagtggca gtccttggat gtgccaagat gcataatctt catggagact ctgaagtaga tggtgccctg gtaaatgaat tatacagttt gctgcgtgac caggatccaa ttgtagttgt gaactgcttg aggtctctag aggaaattct gaaacaggaa ggaggcgttg tcatcaataa gcccattgct caccatctct taaatcgaat gtcaaaactg gaccaatggg gccaggctga agtattgaac tttctgctac gctaccaacc ccgcagtgag gaagaactat ttgacattct caatctgttg gatagtttcc tcaagagcag tagcccaggt gtggtgatgg gagctaccaa actttttctg atcttggcaa aaatgtttcc ccacgtacaa actgatgtcc ttgtgcgggt caagggacct ttgctagctg cctgttcttc agagagccgt gagctctgtt ttgttgctct ttgtcatgta cgccagatct tgcatagttt accaggtcac tttagcagcc actacaaaaa gtttttttgc tcctactcgg agccccacta catcaaacta cagaaagtgg aggtgctgtg tgaactggtg aacgatgaga atgtgcagca ggtgctagag gagcttcgag ggtactgcac ggatgtgtct gcggactttg cacaggctgc catctttgcc ataggtggca ttgccaggac ttacacagat caatgtgttc agattttaac agagttgctg ggtcttcgac aagagcacat taccacagtg gtggtgcaga ctttccgaga cctggtttgg ttgtgtcctc agtgtactga agctgtatgt caggccctgc ccggctgtga agagaacatt caagatagtg aggggaagca agcacttatt tggctacttg gtgtccatgg ggaaagaatt cctaatgctc cttatgtgtt agaggacttt gttgagaatg tgaagtcgga aacatttcca gctgttaaga tggagctgct cactgctttg ctgcgccttt tcctctcccg acctgctgag tgccaggaca tgctaggacg tttgttgtat tactgcatag aggaagaaaa agatatggct gtacgggacc gaggtctctt ctattatcgc ctcctcttag ttggcattga tgaagttaag cggattctgt gtagccctaa atctgaccct actcttggac ttttggagga tccggcagaa agacctgtga atagctgggc ctcagacttc aacacactgg tgccagtgta tggcaaagcc cactgggcaa ctatctctaa atgccagggg gcagagcgtt gtgacccaga gcttcctaaa acttcatcct ttgccgcatc aggacccttg attcctgaag agaacaagga gagggtacaa gaactccctg attctggagc cctcatgcta gtccccaatc gccagcttac tgctgattat tttgagaaaa cttggcttag ccttaaagtt gctcatcagc aagtgttgcc ttggcgggga gaattccatc ctgacaccct ccagatggct cttcaagtag tgaacatcca gaccatcgca atgagtaggg ctgggtctcg gccatggaaa gcatacctca gtgctcagga tgatactggc tgtctgttct taacagaact gctattggag cctggaaact cagaaatgca gatctctgtg aaacaaaatg aagcaagaac ggagacgctg aatagtttta tttctgtatt agaaactgtg attggaacaa ttgaagaaat Protein function: Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways (PubMed:10066790, PubMed:10436028). AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asymmetric localization of somatodendritic proteins in neurons. AP-4 is involved in the recognition and binding of tyrosine-based sorting signals found in the cytoplasmic part of cargos, but may also recognize other types of sorting signal (Probable). [The UniProt Consortium]