ANKRD13D (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pU

Length: 1557 Sequence: ATGGTGCAGC TGGTGCTCCA GTATCGGGAC TACCAGAGGG CCACGCAGAG GCTGGCGGGC ATTCCGGAAC TGCTCAACAA ACTTCGCCAG GCCCCCGATT TCTACGTTGA GATGAAGTGG GAGTTCACCA GCTGGGTGCC CCTTGTGTCT AAGATGTGCC CAAGCGATGT GTACCGCGTG TGGAAGCGGG GTGAGAGCCT GCGAGTAGAC ACCAGTCTCC TGGGCTTCGA GCACATGACC TGGCAGCGGG GCCGGAGGAG CTTCATCTTC AAGGGCCAGG AGGCAGGAGC CCTGGTGATG GAAGTGGACC ATGACCGGCA GGTGGTGCAT GTGGAGACAC TGGGGCTCAC TCTGCAGGAG CCCGAAACAC TGCTGGCCGC CATGCGGCCC AGCGAGGAGC ATGTGGCCAG TCGCCTCACC TCTCCTATCG TCTCCACCCA CCTGGACACT CGTAATGTGG CCTTTGAGAG GAACAAATGT GGTATCTGGG GCTGGCGGTC TGAGAAGATG GAAACTGTTA GCGGCTACGA GGCCAAGGTG TACAGTGCCA CCAACGTGGA GCTGGTGACA CGCACACGCA CGGAGCACCT CTCTGATCAG GACAAGTCGA GGAGCAAAGC GGGGAAGACT CCATTCCAGT CCTTCCTGGG GATGGCGCAG CAGCATTCCT CCCACACCGG GGCCCCCGTG CAGCAGGCAG CCAGCCCCAC CAACCCCACA GCCATCTCCC CTGAGGAGTA CTTCGACCCC AACTTCAGCC TGGAGTCACG GAACATTGGC CGCCCCATCG AGATGTCCAG CAAAGTACAG AGGTTCAAGG CAACACTGTG GCTGAGTGAA GAGCACCCGC TCTCCCTGGG TGACCAGGTG ACCCCCATCA TCGACCTAAT GGCCATCAGC AACGCTCACT TTGCCAAGCT GCGCGACTTC ATCACTCTGC GCCTTCCACC TGGCTTCCCC GTCAAAATTG AGATTCCCCT TTTCCACGTG CTCAATGCCC GCATCACCTT CAGCAACCTG TGTGGCTGTG ATGAGCCCCT GAGCTCCGTG TGGGTGCCGG CCCCCAGCTC TGCTGTCGCC GCATCAGGGA ACCCTTTCCC GTGCGAGGTG GACCCCACCG TGTTTGAAGT GCCCAACGGG TACAGCGTGC TGGGCATGGA GCGCAACGAG CCCCTCCGGG ACGAGGACGA TGACCTCCTG CAGTTCGCCA TCCAGCAGAG CCTGCTTGAA GCGGGCACTG AGGCGGAGCA GGTGACCGTC TGGGAAGCCC TGACCAACAC CCGGCCCGGT GCCCGCCCTC CTCCCCAGGC CACGGTTTAT GAGGAACAGC TTCAGCTGGA GCGGGCCCTC CAGGAAAGCC TGCAGCTGTC CACAGAGCCC AGGGGCCCAG GATCCCCTCC CAGGACACCC CCAGCCCCCG GTCCACCCAG CTTTGAAGAG CAGCTGCGCC TGGCCCTGGA GTTGTCTTCA CGGGAGCAGG AGGAGCGGGA GCGGCGCGGG CAGCAGGAGG AGGAGGACTT ACAGCGGATC CTGCAGCTGT CACTCACTGA Protein function: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane. [The UniProt Consortium]