AKAP5 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 1284 Sequence: ATGGAAACCA CAATTTCAGA AATTCATGTA GAAAACAAGG ATGAGAAGAG ATCAGCAGAA GGTAGTCCTG GGGCTGAAAG GCAGAAGGAA AAGGCATCCA TGCTTTGCTT CAAGAGAAGA AAGAAAGCAG CCAAAGCACT GAAGCCCAAA GCTGGCTCTG AAGCTGCTGA TGTGGCAAGG AAGTGTCCAC AAGAAGCAGG AGCTTCTGAT CAGCCAGAGC CCACACGGGG GGCCTGGGCC TCACTCAAAC GTCTTGTAAC ACGCAGGAAA AGGTCAGAGT CTTCAAAGCA GCAAAAGCCA TTGGAGGGTG AAATGCAACC TGCAATAAAT GCTGAGGATG CTGATCTTTC TAAGAAAAAG GCAAAATCTA GACTTAAGAT TCCCTGCATA AAATTCCCAA GAGGGCCAAA AAGGAGTAAT CATTCCAAAA TTATAGAAGA CTCAGACTGC AGCATCAAAG TCCAGGAAGA AGCTGAAATT TTGGATATAC AAACACAGAC CCCATTGAAT GATCAGGCAA CAAAGGCTAA GTCAACCCAG GATCTAAGTG AAGGCATCTC ACGGAAAGAT GGTGATGAGG TCTGTGAATC AAATGTGAGC AATAGCATAA CTTCTGGAGA GAAAGTGATT TCAGTAGAAC TTGGATTAGA TAATGGGCAT TCTGCTATTC AAACGGGAAC TCTAATCCTT GAAGAAATTG AAACGATCAA GGAAAAACAA GATGTTCAAC CCCAGCAAGC AAGCCCACTT GAAACTTCAG AAACAGACCA TCAGCAGCCA GTACTTTCTG ATGTTCCTCC TTTACCTGCA ATTCCAGATC AACAAATTGT GGAAGAAGCC AGTAACAGTA CCCTAGAAAG TGCACCAAAT GGAAAAGACT ATGAAAGTAC AGAGATTGTA GCTGAAGAAA CTAAGCCAAA AGATACTGAA TTGAGCCAAG AATCAGATTT TAAAGAAAAT GGGATCACTG AAGAGAAATC CAAATCAGAA GAAAGCAAAA GAATGGAGCC AATTGCTATT ATTATTACAG ACACTGAAAT CAGTGAATTT GATGTTACAA AATCTAAAAA TGTCCCTAAG CAATTCTTAA TTTCAGCTGA AAATGAGCAA GTAGGGGTTT TTGCTAATGA TAATGGTTTT GAGGATAGAA CTTCAGAACA ATATGAAACA CTCTTAATTG AAACAGCCTC TTCTCTAGTC AAGAATGCTA TTCAGTTGTC AATAGAACAG CTGGTTAATG AAATGGCCTC TGATGATAAT AAAATAAACA ATCTTCTACA Protein function: Multivalent scaffold protein that anchors the cAMP-dependent protein kinase/PKA to cytoskeletal and/or organelle-associated proteins, targeting the signal carried by cAMP to specific intracellular effectors (PubMed:1512224). Association with the beta2- adrenergic receptor (beta2-AR) not only regulates beta2-AR signaling pathway, but also the activation by PKA by switching off the beta2-AR signaling cascade. Plays a role in long term synaptic potentiation by regulating protein trafficking from the dendritic recycling endosomes to the plasma membrane and controlling both structural and functional plasticity at excitatory synapses (PubMed:25589740). [The UniProt Consortium]