AKAP10 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 1989 Sequence: atgaggggag ccgggccctc cccgcgccag tccccccgca ccctccgtcc cgacccgggc cccgccatgt ccttcttccg gcggaaagtg aaaggcaaag aacaagagaa gacctcagat gtgaagtcca ttaaagcttc aatatccgta cattccccac aaaaaagcac taaaaatcat gccttgctgg aggctgcagg accaagtcat gttgcaatca atgccatttc tgccaacatg gactcctttt caagtagcag gacagccaca cttaagaagc agccaagcca catggaggcc gctcattttg gtgacctggg cagatcttgt ctggactacc agactcaaga gaccaaatca agcctttcta agacccttga acaagtcttg cacgacacta ttgtcctccc ttacttcatt caattcatgg aacttcggcg aatggagcat ttggtgaaat tttggttaga ggctgaaagt tttcattcaa caacttggtc gcgaataaga gcacacagtc taaacacagt gaagcagagc tcactggctg agcctgtctc tccatctaaa aagcatgaaa ctacagcgtc ttttttaact gattctcttg ataagagatt ggaggattct ggctcagcac agttgtttat gactcattca gaaggaattg acctgaataa tagaactaac agcactcaga atcacttgct gctttcccag gaatgtgaca gtgcccattc tctccgtctt gaaatggcca gagcaggaac tcaccaagtt tccatggaaa cccaagaatc ttcctctaca cttacagtag ccagtagaaa tagtcccgct tctccactaa aagaattgtc aggaaaacta atgaaaagta tagaacaaga tgcagtgaat acttttacca aatatatatc tccagatgct gctaaaccaa taccaattac agaagcaatg agaaatgaca tcatagcaag gatttgtgga gaagatggac aggtggatcc caactgtttc gttttggcac agtccatagt ctttagtgca atggagcaag agcactttag tgagtttctg cgaagtcacc atttctgtaa ataccagatt gaagtgctga ccagtggaac tgtttacctg gctgacattc tcttctgtga gtcagccctc ttttatttct ctgagtacat ggaaaaagag gatgcagtga atatcttaca attctggttg gcagcagata acttccagtc tcagcttgct gccaaaaagg gccaatatga tggacaggag gcacagaatg atgccatgat tttatatgac aagtacttct ccctccaagc cacacatcct cttggatttg atgatgttgt acgattagaa attgaatcca atatctgcag ggaaggtggg ccactcccca actgtttcac aactccatta cgtcaggcct ggacaaccat ggagaaggtc tttttgcctg gctttttgtc cagcaatctt tattataaat atttgaatga tctcatccat tcggttcgag gagatgaatt tctgggcggg aacgtgtcgc tgactgctcc tggctctgtt ggccctcctg atgagtctca cccagggagt tctgacagct ctgcgtctca gtccagtgtg aaaaaagcca gtattaaaat actgaaaaat tttgatgaag cgataattgt ggatgcggca agtctggatc cagaatcttt atatcaacgg acatatgccg ggaagatgac atttggaaga gtcagtgact tggggcaatt catccgagaa tctgagcctg aacctgatgt aaggaaatca aaaggatcca tgttctcaca agctatgaag aaatgggtgc aaggaaatac tgatgaggcc caggaagagc tagcttggaa gattgctaaa atgatagtca gtgacattat gcagcaggct cagtatgatc aaccgttaga gaaatctaca Protein function: Differentially targeted protein that binds to type I and II regulatory subunits of protein kinase A and anchors them to the mitochondria or the plasma membrane. Although the physiological relevance between PKA and AKAPS with mitochondria is not fully understood, one idea is that BAD, a proapoptotic member, is phosphorylated and inactivated by mitochondria-anchored PKA. It cannot be excluded too that it may facilitate PKA as well as G protein signal transduction, by acting as an adapter for assembling multiprotein complexes. With its RGS domain, it could lead to the interaction to G- alpha proteins, providing a link between the signaling machinery and the downstream kinase. [The UniProt Consortium]