ADCY10 (Vector pUC, Accession No. BC117366)

Length: 4833 Sequence: atgaacactc caaaagaaga attccaggac tggcccatag tcagaatagc agctcattta ccagacctca ttgtctatgg acatttctcc ccagagcgac cctttatgga ttattttgac ggagtcctga tgtttgttga tatttcaggt tttactgcaa tgactgagaa gttcagcagt gccatgtaca tggacagagg ggctgagcag ttggtggaga tcctcaacta ccacataagt gcaatagtgg agaaagtgtt gatttttgga ggagacatcc tgaaatttgc aggtgatgca ctgctagccc tgtggagggt ggagcgaaag cagctgaaaa acattatcac agtggtaatt aaatgtagcc tggagatcca tggattgttt gagacccagg agtgggaaga aggcctagac atccgagtca agataggact ggctgctggc cacatcagca tgttggtctt tggagatgaa acacacagcc actttctggt gattggtcag gcagtggacg atgtgcgcct tgcccagaac atggctcaga tgaatgatgt tattctgtca ccaaactgct ggcagctctg tgaccggagc atgattgaaa ttgagagtgt tccagatcag agagcagtta aggttaactt cttaaaacca ccccccaatt ttaattttga tgaatttttc acaaagtgta cgaccttcat gcattattat ccttctggtg agcacaaaaa cctcctgagg cttgcatgca cgctgaagcc tgatcctgaa ctggagatgt ccctacaaaa gtatgtgatg gaaagcattt tgaagcagat tgataacaaa cagcttcagg gctatttatc tgagcttcgc ccagtgacga ttgtgtttgt gaacctgatg tttgaagacc aagacaaagc agaagagata ggcccagcca tccaggatgc ctatatgcac atcacttctg tcctgaagat cttccaaggc caaatcaata aagtcttcat gtttgacaag ggctgctctt tcctctgtgt ctttggcttc cctggggaaa aggtacctga cgagctcact catgctctgg aatgtgctat ggatatattt gacttctgct ctcaagtcca caaaatccaa actgtatcca tcggtgttgc cagtgggatt gtcttctgtg ggatcgttgg acacactgtg agacacgagt acacagtcat tggtcaaaaa gtcaacttag ctgccaggat gatgatgtac tacccaggaa ttgtgacctg cgactctgtc acctacaatg ggagcaacct accagcgtac ttttttaaag agcttccaaa gaaagttatg aaaggtgttg cagattctgg accattgtat cagtattggg gccgtactga gaaagtcatg tttggtatgg cgtgcctcat ctgcaacaga aaggaggatt accctttgct gggacgtaat aaagagatca actacttcat gtatactatg aagaaatttt tgatatctaa cagcagccaa gtcttaatgt atgagggatt accaggatat ggaaaaagcc agatacttat gaaaattgag tacctggccc aaggtaagaa tcacaggatt attgccattt cattgaataa gatcagcttc catcaaactt tctataccat ccagatgttc atggccaatg tcctaggcct agacacttgt aaacattata aagaacgaca gaccaacctt cgaaataaag tcatgacact gttggatgaa aagttctact gtcttcttaa tgacattttc catgttcagt tccctatttc tcgggagatt tccaggatga gcaccttgaa aaagcaaaaa caattggaaa tattgtttat gaagatcttg aagctgatag tgaaagagga aaggattatt tttatcattg atgaggccca gtttgtggat tcgacctcct ggagatttat ggagaagctt atccggactc ttcctatctt catcattatg tccctgtgtc ccttcgttaa cattccctgt gcagctgcca gggccgtaat aaagaacagg aacaccacct acattgtcat tggtgcagta cagcctaacg acatctccaa caagatctgt cttgacctca atgtgagctg catctccaaa gaactggact cgtacctggg ggagggaagc tgtgggattc cattttactg tgaagaattg cttaaaaacc tggaacatca tgaggtactc gttttccaac aaacggagtc tgaggaaaag acaaatagga cctggaataa cctgttcaag tattccatta agctaacaga gaagttaaac atggttactc tccatagtga taaggaaagt gaagaagtct gtcacctcac aagtggcgtc agactgaaaa acctgtcacc tccaacgtca ttaaaagaaa tctctctgat ccagctggat agcatgagac tttcccacca aatgctggtg agatgtgctg ccatcattgg cctgaccttc accactgagt tgttgtttga gattctcccc tgttggaata tgaagatgat gatcaagacc ctggcaaccc tagtggaatc taacattttt tattgtttcc ggaatggcaa ggagcttcaa aaggccctga aacagaatga tccctcattt gaggtgcact atcgttcctt gtctctgaag cccagtgaag ggatggatca cggtgaagag gaacagcttc gtgaactgga gaatgaggtg atcgagtgcc acaggattcg attctgtaac cctatgatgc agaaaacagc ctacgagctg tggctcaagg accagagaaa agccatgcac ttgaaatgtg cccgcttttt agaagaagat gcccacagat gtgaccactg ccgaggcagg gacttcattc cctatcatca cttcacagtg aatattcggc tcaacgcttt agacatggat gccattaaaa agatggctat gtctcatgga tttaaaactg aagaaaagct tatcttgtcc aactcagaga ttcctgagac atctgcattt tttcctgaaa atcgcagtcc tgaagaaata agagaaaaga tcttgaattt ctttgaccac gttttaacaa aaatgaagac atctgacgaa gacattatcc ctctggaatc ttgccagtgt gaagaaatcc tagagattgt catcttgcct ctggcccacc attttctggc tttgggagaa aatgacaaag ccttatatta cttcttagaa attgcatctg cttatctcat cttttgtgat aactacatgg catacatgta tttgaatgaa ggacagaagt tgctaaaaac tctcaagaag gacaaatctt ggagccagac atttgagtct gccacctttt acagcctcaa aggtgaggtc tgtttcaata tgggccagat agtgcttgcc aagaaaatgc tgaggaaggc actgaagctc ctcaaccgaa tctttcctta caacttaatc tccttgtttc tccatatcca tgtcgagaaa aacagacact ttcattatgt gaatcggcag gcccaagaga gcccacctcc agggaagaag aggctggcac aactttaccg gcaaactgtc tgcctttcct tgctgtggcg catctatagc tacagttatc tttttcactg caagtattat gcccacctgg cagttatgat gcaaatgaat actgcactgg aaactcaaaa ttgtttccag atcattaagg cttacctaga ctattcgcta taccaccacc tggctggcta caaaggtgtg tggttcaaat atgaagtcat ggccatggag cacatcttca acctccccct gaaaggcgag ggcattgaaa tcgtggcata cgtggctgag acactggtct tcaacaagct cataatggga cacctggatt tggccattga gttaggctcc cgagcccttc agatgtgggc actgctccag aatcccaacc gacattatca gtccctctgc agacttagca gatgtctcct tctgaacagc agatacccgc aattgatcca ggtgctgggg cggctgtggg agctttctgt aacacaggaa cacatcttca gcaaggcatt tttctatttt gtctgcttgg acatcctgct ttattctggt tttgtttata gaacatttga agaatgtttg gaattcatac accaatacga aaacaacaga atcctcaagt tccacagtgg actcctcctg ggactttatt cctctgtagc tatctggtat gccagacttc aggaatggga caacttttac aaattttcca atagagctaa aaatcttttg ccaagaagaa ccatgacact tacttactat gacggaatat ctaggtacat ggaggggcaa gttcttcacc ttcaaaaaca aatcaaagaa cagtcagaga atgcccaagc cagtggggag gagctactca agaacttgga gaatctggtg gctcaaaata ccactggccc tgtcttttgc ccaaggctct accacctgat ggcttacgtc tgtatattaa tgggagatgg gcagaaatgt ggcctcttcc tgaacacagc cttgcggctc tctgaaacac aggggaatat actggagaaa tgctggctga acatgaacaa agaatcatgg tactcaacct ctgagttaaa agaagaccaa tggcttcaga cgatcttgag tctcccatca tgggaaaaaa ttgtagcagg cagggtaaac attcaggatc ttcaaaaaaa caaattcctg atgagagcta ataccgtgga caatcatttc Protein function: Catalyzes the formation of the signaling molecule cAMP (PubMed:12609998, PubMed:15659711, PubMed:24616449, PubMed:25040695, PubMed:24567411). May function as sensor that mediates responses to changes in cellular bicarbonate and CO(2) levels (PubMed:15659711, PubMed:17591988). Has a critical role in mammalian spermatogenesis by producing the cAMP which regulates cAMP-responsive nuclear factors indispensable for sperm maturation in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization. Involved in ciliary beat regulation (PubMed:17591988). [The UniProt Consortium]