A4GALT (Vector pUC, Accession No. BC017068)

Length: 1062 Sequence: atgtccaagc cccccgacct cctgctgcgg ctgctccggg gcgccccaag gcagcgggtc tgcaccctgt tcatcatcgg cttcaagttc acgtttttcg tctccatcat gatctactgg cacgttgtgg gagagcccaa ggagaaaggg cagctctata acctgccagc agagatcccc tgccccacct tgacaccccc caccccaccc tcccacggcc ccactccagg caacatcttc ttcctggaga cttcagaccg gaccaacccc aacttcctgt tcatgtgctc ggtggagtcg gccgccagaa ctcaccccga atcccacgtg ctggtcctga tgaaagggct tccgggtggc aacgcctctc tgccccggca cctgggcatc tcacttctga gctgcttccc gaatgtccag atgctcccgc tggacctgcg ggagctgttc cgggacacac ccctggccga ctggtacgcg gccgtgcagg ggcgctggga gccctacctg ctgcccgtgc tctccgacgc ctccaggatc gcactcatgt ggaagttcgg cggcatctac ctggacacgg acttcattgt tctcaagaac ctgcggaacc tgaccaacgt gctgggcacc cagtcccgct acgtcctcaa cggcgcgttc ctggccttcg agcgccggca cgagttcatg gcgctgtgca tgcgggactt cgtggaccac tacaacggct ggatctgggg tcaccagggc ccgcagctgc tcacgcgggt cttcaagaag tggtgttcca tccgcagcct ggccgagagc cgcgcctgcc gcggcgtcac caccctgccc cctgaggcct tctaccccat cccctggcag gactggaaga agtactttga ggacatcaac cccgaggagc tgccgcggct gctcagtgcc acctatgctg tccacgtgtg gaacaagaag agccagggca cgcggttcga ggccacgtcc agggcactgc tggcccagct gcatgcccgc tactgcccca cgacgcacga ggccatgaaa atgtacttgt Protein function: Catalyzes the transfer of galactose from UDP-alpha-D- galactose to lactosylceramide/beta-D-galactosyl-(1->4)-beta-D-glucosyl- (1<->1)-ceramide(d18:1(4E)) to produce globotriaosylceramide/globoside Gb3Cer (d18:1(4E)) (PubMed:10748143). Also able to transfer galactose to galactosylceramide/beta-D-Gal-(1<->1')-Cer (PubMed:10748143). Globoside Gb3Cer is a glycosphingolipid of the globo serie, one of the major types of neutral root structures of glycosphingolipids, that constitute a significant portion of mammalian cell membranes (Probable). Globotriaosylceramide/globoside Gb3Cer in blood and tissue cell membranes is the antigen Pk of blood histogroup P (PubMed:10747952). [The UniProt Consortium]