Lithocholic Acid (CRM)

Lithocholic acid (CRM) (Cay44907) is a certified reference material categorized as a secondary bile acid. Exogenously administered lithocholic acid induces cholestasis and hepatoxicity in animals. Plasma levels of lithocholic acid are increased in patients with Alzheimer's disease but not patients with mild cognitive impairment. Lithocholic acid is secreted at lower amounts from patients with coronary artery disease (CAD) than from individuals without CAD. This product is intended for use in quantitative analytical research applications. This product is also available as a general research tool (Cay20253).. SMILES: C[C@H](CCC(O)=O)[C@@]1([H])CC[C@@]2([H])[C@]3([H])CC[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C. InChi Code: InChI=1S/C24H40O3/c1-15(4-9-22(26)27)19-7-8-20-18-6-5-16-14-17(25)10-12-23(16,2)21(18)11-13-24(19,20)3/h15-21,25H,4-14H2,1-3H3,(H,26,27)/t15-,16-,17-,18+,19-,20+,21+,23+,24-/m1/s1. InChi Key: SMEROWZSTRWXGI-HVATVPOCSA-N