JWH 203 N-(4-hydroxypentyl) metabolite-d5

JWH 203 N-(4-hydroxypentyl) metabolite-d5 contains five deuterium atoms at the 2, 4 ,5, 6, and 7 positions. It is intended for use as an internal standard for the quantification of JWH 203 N-(4-hydroxypentyl) metabolite by GC- or LC-mass spectrometry. JWH 203 (Cay-9000736) is an analgesic chemical from the phenylacetylindole family that acts as an agonist with Ki values of 8.0 and 7.0 nM at the central cannabinoid (CB1) and peripheral (CB2) receptors, respectively. Similar to the related 2'-methoxy compound JWH 250 (Cay-13634), JWH 203 has a phenylacetyl group in place of the naphthoyl ring used in most aminoalkylindole cannabinoid compounds. Compared to JWH 250, JWH 203 displays slightly more potent binding affinities for the CB1 and CB2 receptors (JWH 250 Kis = 11 and 33 nM, respectively). JWH 203 N-(4-hydroxypentyl) metabolite is expected to be a metabolite of JWH 203 that would be detectable both in serum and in urine. While similar hydroxylated phase I metabolites of synthetic CBs retain activity, the physiological properties of this compound have yet to be determined. This product is intended for research and forensic applications.Formal Name: 2-(2-chlorophenyl)-1-(1-(4-hydroxypentyl)-1H-indol-3-yl-2,4,5,6,7-d5)ethan-1-one. CAS Number: 2747915-98-4. Molecular Formula: C21H17D5ClNO2. Formula Weight: 360.9. Purity: >99% deuterated forms (d1-d5). Formulation: (Request formulation change), A solution in methyl acetate. Solubility: DMF: 10 mg/ml, DMSO: 5 mg/ml. lambdamax: 212, 245, 304 nm. SMILES: O=C(CC1=C(Cl)C=CC=C1)C2=C([2H])N(CCCC(O)C)C3=C2C([2H])=C([2H])C([2H])=C3[2H]. InChi Code: InChI=1S/C21H22ClNO2/c1-15(24)7-6-12-23-14-18(17-9-3-5-11-20(17)23)21(25)13-16-8-2-4-10-19(16)22/h2-5,8-11,14-15,24H,6-7,12-13H2,1H3/i3D,5D,9D,11D,14D. InChi Key: ALUOSHHIHVCMCU-QMJOWLLBSA-N.