JWH 073 N-(4-hydroxybutyl) metabolite-d5

JWH 073 N-(4-hydroxybutyl) metabolite-d5 (Cay-10934) is intended for use as an internal standard for the quantification of JWH 073 N-(4-hydroxybutyl) metabolite (Cay-9000865) by GC- or LC-MS. JWH 073 is a mildly selective agonist of the central cannabinoid (CB1) receptor derived from the aminoalkylindole WIN 55,212-2. The Ki values for binding CB1 and the peripheral cannabinoid (CB2) receptor are 8.9 and 38 nM, respectively for a CB1:CB2 ratio of 0.23. JWH 073 is one of several synthetic CBs which have been included in smoking mixtures. JWH 073 N-(4-hydroxybutyl) metabolite is expected to be a major urinary metabolite of JWH 073, characterized by monohydroxylation of the N-alkyl chain, based on the metabolism of the closely-related JWH 015 and JWH 018. In urine samples, this metabolite of JWH 018 is almost completely glucuronidated.Formal Name: (1-(4-hydroxybutyl)-1H-indol-3-yl-2',4',5',6',7'-d5)(naphthalen-1-yl)-methanone. CAS Number: 2484976-96-5. Molecular Formula: C23H16D5NO2. Formula Weight: 348.5. Purity: >99% deuterated forms (d1-d5). Formulation: (Request formulation change), A solution in methanol. Solubility: DMF: 30 mg/ml, DMF:PBS (pH 7.2) (1:9): 0.1 mg/ml, DMSO: 30 mg/ml, Ethanol: 0.5 mg/ml. lambdamax: 218, 247, 314 nm. SMILES: O=C(C1=C([2H])N(CCCCO)C2=C([2H])C([2H])=C([2H])C([2H])=C12)C3=CC=CC4=C3C=CC=C4. InChi Code: InChI=1S/C23H21NO2/c25-15-6-5-14-24-16-21(19-11-3-4-13-22(19)24)23(26)20-12-7-9-17-8-1-2-10-18(17)20/h1-4,7-13,16,25H,5-6,14-15H2/i3D,4D,11D,13D,16D. InChi Key: FIBVDFAPDNJBNI-HXXXRZHPSA-N.