Fipronil-13C2,15N2

Fipronil-13C2,15N2 is intended for use as an internal standard for the quantification of fipronil (Cay-24128) by GC- or LC-MS. Fipronil is an insecticide that acts as a selective antagonist of insect GABA receptors (IC50s = 28 and 1,660 nM for cockroach and rat receptors, respectively). It also inhibits desensitizing and non-desensitizing glutamate-induced chloride currents in cockroach neurons (IC50s = 800 and 10 nM, respectively). Fipronil induces activity of the cytochrome P450 (CYP) isoforms CYP1A1/2, CYP2B1/2, and CYP3A1/2 in isolated rat liver microsomes. Formulations containing fipronil have been used as insecticides in veterinary care.Formal Name: 5-(amino-15N)-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-((trifluoromethyl)sulfinyl)-1H-pyrazole-5-13C-3-carbonitrile-13C-15N. Molecular Formula: C10[13C]2H4Cl2F6N2[15N]2OS. Formula Weight: 441.1. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMSO: sparingly soluble, Methanol: slightly soluble. SMILES: ClC1=C(N2N=C([13C]#[15N])C(S(C(F)(F)F)=O)=[13C]2[15NH2])C(Cl)=CC(C(F)(F)F)=C1. InChi Code: InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2/i3+1,10+1,21+1,22+1. InChi Key: ZOCSXAVNDGMNBV-LGNNNXBFSA-N.