11-deoxy Cortisol-d2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
Cay45693-1	1 mg		-		5 - 10 business days*		549.00€

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11-deoxy Cortisol-d2 is intended for use as an internal standard for the quantification of... more

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Product information "11-deoxy Cortisol-d2"

11-deoxy Cortisol-d2 is intended for use as an internal standard for the quantification of 11-deoxy cortisol by GC- or LC-MS. 11-deoxy Cortisol is a precursor in the biosynthesis of cortisol (hydrocortisone, Item No. 20739). It is converted into cortisol by the cytochrome P450 (CYP) isoform CYP11B1, also known as 11beta-hydroxylase. Urinary levels of 11-deoxy cortisol and the ratio of 11-deoxy cortisol to cortisol are elevated in patients with 11beta-hydroxylase deficiency, a type of congenital adrenal hyperplasia (CAH) characterized by cortisol deficiency and hypertension.. SMILES: O=C1CC[C@@]2(C)C(CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4(O)C(C([2H])([2H])O)=O)=C1. InChi Code: InChI=1S/C21H30O4/c1-19-8-5-14(23)11-13(19)3-4-15-16(19)6-9-20(2)17(15)7-10-21(20,25)18(24)12-22/h11,15-17,22,25H,3-10,12H2,1-2H3/t15-,16+,17+,19+,20+,21+/m1/s1/i12D2. InChi Key: WHBHBVVOGNECLV-FAWVBKBISA-N

Keywords:	Compound S, Cortexolone, Cortodoxone, Reichstein's Substance S, 17,21-dihydroxy-pregn-4-ene-3,20-dione-21,21-d2
Supplier:	Cayman Chemical
Supplier-Nr:	45693

Properties

Application:	GC-MS, LC-MS internal standard, quantification, cortisol biosynthesis precursor
MW:	348.48 D
Formula:	C21H28D2O4
Purity:	>99% deuterated forms (d1-d2)
Format:	Solution