trans-Vaccenic Acid (sodium salt)

trans-Vaccenic acid is an omega-7 fatty acid that has been found in bovine milk fats. Dietary administration of trans-vaccenic acid (1% w/w) reduces total body fat, mesenteric fat, and adipocyte size, increases inguinal fat mass, and decreases intestinal and hepatic triglyceride secretion in a rat model of obesity with features of metabolic syndrome. It decreases hepatocellular ballooning and steatosis, markers of non-alcoholic fatty liver disease (NAFLD), in the same model. Dietary administration of a butter enriched with trans-vaccenic acid decreases serum cholesterol levels and the formation of aortic atherosclerotic lesions in Ldlr-/- mice. InChI: InChI=1S/C18H34O2.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20,/h7-8H,2-6,9-17H2,1H3,(H,19,20),/q,+1/p-1/b8-7+, InChIKey: NKZQDAISLCDHHU-USRGLUTNSA-M SMILES: [O-]C(CCCCCCCCC/C=C/CCCCCC)=O.[Na+]