tetranor-PGEM-d6

tetranor-Prostaglandin E metabolite-d6 (tetranor-PGEM-d6) is intended for use as an internal standard for the quantification of tetranor-PGEM (Cay-14840) by GC- or LC-MS. tetranor-PGEM is the major urinary metabolite of PGE2 (Cay-14010). Urine levels of tetranor-PGEM are increased in patients with diabetic nephropathy. Increased urine levels are also associated with a higher risk of breast cancer in postmenopausal women with a body mass index (BMI) of less than 25 kg/m2.Formal Name: (1R,2R,5R)-2-(2-carboxyethyl)-5-hydroxy-epsilon,3-dioxo-cyclopentaneoctanoic-alpha,alpha,beta,beta,gamma,gamma-d6 acid. CAS Number: 1240398-16-6. Synonyms: tetranor-Prostaglandin E Metabolite-d6. Molecular Formula: C16H18D6O7. Formula Weight: 334.4. Purity: >99% deuterated forms (d1-d6). Formulation: (Request formulation change), A solution in methyl acetate. Solubility: DMF: 50 mg/ml, DMSO: 50 mg/ml, Ethanol: Not Stable, PBS (pH 7.2): 1 mg/ml. SMILES: O=C1[C@H](CCC(O)=O)[C@@H](CCC(CC([2H])([2H])C([2H])([2H])C([2H])([2H])C(O)=O)=O)[C@H](O)C1. InChi Code: InChI=1S/C16H24O7/c17-10(3-1-2-4-15(20)21)5-6-11-12(7-8-16(22)23)14(19)9-13(11)18/h11-13,18H,1-9H2,(H,20,21)(H,22,23)/t11-,12-,13-/m1/s1/i1D2,2D2,4D2. InChi Key: ZJAZCYLYLVCSNH-VFBFAAMGSA-N.