tetranor-PGAM

Prostaglandin E2 (PGE2), one of the most widely investigated PGs, can be used as a biomarker of inflammation, disease state, or therapeutic effectiveness. However due to its rapid metabolism, direct measurement of PGE2 in biological samples is difficult. The major urinary metabolite of PGE2, tetranor-PGEM, serves as an indirect marker of PGE2 biosynthesis.{2127, 2308} Though like PGE2, tetranor-PGEM is also chemically unstable. tetranor-PGAM is a dehydration product of tetranor-PGEM and can be measured as a surrogate for tetranor-PGEM levels in urine.Formal Name: 5R-(2-carboxyethyl)-epsilon,4-dioxo-2-cyclopentene-1S-octanoic acid. CAS Number: 52510-53-9. Synonyms: tetranor-Prostaglandin A Metabolite. Molecular Formula: C16H22O6. Formula Weight: 310.3. Purity: >98%. Formulation: (Request formulation change), A solution in methyl acetate. Solubility: DMF: 50 mg/ml, DMSO: 50 mg/ml, Ethanol: 50 mg/ml, PBS (pH 7.2): 1 mg/ml. SMILES: O=C1[C@H](CCC(O)=O)[C@@H](CCC(CCCCC(O)=O)=O)C=C1. InChi Code: InChI=1S/C16H22O6/c17-12(3-1-2-4-15(19)20)7-5-11-6-9-14(18)13(11)8-10-16(21)22/h6,9,11,13H,1-5,7-8,10H2,(H,19,20)(H,21,22)/t11-,13+/m0/s1. InChi Key: HYPIFMOQVFWSBF-WCQYABFASA-N.