Stearoyl-L-carnitine (chloride)

Stearoyl-L-carnitine is a naturally occurring long-chain acylcarnitine. It inhibits sodium-dependent [3H]carnitine uptake in human proximal convoluted tubular (HPCT) cells by 52% when used at a concentration of 500 µM. It also inhibits lecithin:cholesterol acyltransferase activity in rat, but not human, plasma when used at a concentration of 500 µM/ml of plasma. Plasma levels of stearoyl-L-carnitine are decreased in patients with chronic fatigue syndrome and increased in patients with end-stage renal disease.Formal Name: 3-carboxy-N,N,N-trimethyl-2R-[(1-oxooctadecyl)oxy]-1-propanaminium, monochloride. CAS Number: 32350-57-5. Synonyms: CAR 18:0, C18:0 Carnitine, Octadecanoyl-L-carnitine, L-Carnitine octdecanoyl ester, L-Carnitine stearoyl ester, L-Octadecanoylcarnitine, L-Stearoylcarnitine, R-Stearoyl carnitine. Molecular Formula: C25H50NO4 . Cl. Formula Weight: 464.1. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMSO: 14 mg/ml, Ethanol: 20 mg/ml. SMILES: OC(C[C@H](C[N+](C)(C)C)OC(CCCCCCCCCCCCCCCCC)=O)=O.[Cl-]. InChi Code: InChI=1S/C25H49NO4.ClH/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-25(29)30-23(21-24(27)28)22-26(2,3)4,/h23H,5-22H2,1-4H3,1H/t23-,/m1./s1. InChi Key: YSVYWVPJJXVIFM-GNAFDRTKSA-N. Side Chain Carbon Sum: 18:0.