(R)-alpha-Lipoic Acid

(R)-alpha-Lipoic Acid
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay27299-1 1 g -

6 - 10 business days*

44.00€
Cay27299-5 5 g -

6 - 10 business days*

117.00€
Cay27299-10 10 g -

6 - 10 business days*

191.00€
Cay27299-25 25 g -

6 - 10 business days*

365.00€
 
(R)-alpha-Lipoic acid is the naturally occurring enantiomer of lipoic acid, a cyclic disulfide... more
Product information "(R)-alpha-Lipoic Acid"
(R)-alpha-Lipoic acid is the naturally occurring enantiomer of lipoic acid, a cyclic disulfide antioxidant. It acts as a cofactor in 2-oxo dehydrogenase complex reactions, where it is reduced to dihydrolipoic acid (DHLA, Cay-16372). (R)-alpha-Lipoic acid (100 mg/kg per day) decreases serum levels of malondialdehyde (MDA) and increases the activity of superoxide dismutase (SOD) and total antioxidative capabilities (T-AOC) in a mouse model of accelerated senescence induced by D-galactose (Cay-20890). It also reduces the escape latency in the Morris water maze compared to both D-galactose and vehicle control groups and rescues decreases in neural progenitor cell proliferation in the hippocampal dentate gyrus.Formal Name: (3R)-1,2-dithiolane-3-pentanoic acid. CAS Number: 1200-22-2. Synonyms: (R)-(+)-Lipoic Acid. Molecular Formula: C8H14O2S2. Formula Weight: 206.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 30 mg/ml, Ethanol:PBS (pH 7.2) (1:8): 0.25 mg/ml. lambdamax: 331 nm. SMILES: O=C(CCCC[C@H]1SSCC1)O. InChi Code: InChI=1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10)/t7-/m1/s1. InChi Key: AGBQKNBQESQNJD-SSDOTTSWSA-N.
Keywords: (R)-(+)-Lipoic Acid, (3R)-1,2-dithiolane-3-pentanoic acid
Supplier: Cayman Chemical
Supplier-Nr: 27299

Properties

Application: Naturally occurring enantiomer, cyclic disulfide antioxidant
MW: 206.3 D
Formula: C8H14O2S2
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 1200-22-2| Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H302, H315, H319, H335
P Phrases: P261, P264, P270, P271, P280, P312, P321, P330, P301+P310, P302+P352, P304+P340, P305+P351+P338, P332+P313, P337+P313, P362+P364, P405, P403+P233, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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