PtdIns-(3,4,5)-P3 (1,2-dioctanoyl) (sodium salt)

PtdIns-(3,4,5)-P3 (1,2-dioctanoyl) (sodium salt)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10007764-100 100 µg -

5 - 10 business days*

59.00€
Cay10007764-500 500 µg -

5 - 10 business days*

265.00€
Cay10007764-1 1 mg -

5 - 10 business days*

470.00€
 
The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane... more
Product information "PtdIns-(3,4,5)-P3 (1,2-dioctanoyl) (sodium salt)"
The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(3,4,5)-P3 (1,2-dioctanoyl) is a synthetic analog of natural phosphatidylinositol (PtdIns) featuring C8:0 fatty acids at the sn-1 and sn-2 positions. The compound features the same inositol and diacylglycerol (DAG) stereochemistry as the natural compound. The short fatty acid chains of this analog give it different physical properties including high solubility in aqueous media compared to naturally occurring PtdIns-(3,4,5)-P3. PtdIns are phosphorylated to mono- (PtdIns-P, PIP), di- (PtdIns-P2, PIP2), and triphosphates (PtdIns-P3, PIP3). Phosphorylation of PtdIns-(4,5)-P2 by phosphoinositide (PI)-3-kinase initiates an intricate signalling cascade at the fore front of scientific research. Formal Name: 1-(1,2-dioctanoylphosphatidyl)inositol-3,4,5-trisphosphate, tetrasodium salt. Synonyms: DOPI-3,4,5-P3, Phosphatidylinositol-3,4,5-trisphosphate. Molecular Formula: C25H46O22P4 . 4Na. Formula Weight: 914.5. Purity: >98%. Formulation: A lyophilized powder. SMILES: O=C(OC[C@H](COP(O[C@@H]1[C@H](O)[C@H](O[P+]([O-])(O)=O)[C@@H](OP([O-])(O)=O)[C@H](OP([O])(O)=O)[C@H]1O)([O-])=O)OC(CCCCCCC)=O)CCCCCCC.[Na+].[Na].[Na+].[Na]. InChi Code: InChI=1S/C25H50O22P4.4Na/c1-3-5-7-9-11-13-18(26)41-15-17(43-19(27)14-12-10-8-6-4-2)16-42-51(39,40)47-22-20(28)23(44-48(30,31)32)25(46-50(36,37)38)24(21(22)29)45-49(33,34)35,,,,/h17,20-25,28-29H,3-16H2,1-2H3,(H,39,40)(H2,30,31,32)(H2,33,34,35)(H2,36,3. InChi Key: HKEJKRRMHQTDJY-JQCOAGCCSA-J. Side Chain Carbon Sum: 16:0.
Keywords: DOPI-3,4,5-P3, Phosphatidylinositol-3,4,5-trisphosphate, 1-(1,2-dioctanoylphosphatidyl)inositol-3,4,5-trisphosphate, tetrasodium salt
Supplier: Cayman Chemical
Supplier-Nr: 10007764

Properties

Application: Bioactive lipid assays
MW: 914.5 D
Formula: C25H46O22P4 . 4Na
Purity: >98%
Format: Solid

Database Information

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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