Prostaglandin I2 (sodium salt)

Prostaglandin I2 (sodium salt)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay18220-1 1 mg -

3 - 10 business days*

74.00€
Cay18220-5 5 mg -

3 - 10 business days*

333.00€
Cay18220-10 10 mg -

3 - 10 business days*

554.00€
Cay18220-25 25 mg -

3 - 10 business days*

1,292.00€
 
Prostaglandin I2 (PGI2) is an unstable cyclooxygenase metabolite detected first in vascular... more
Product information "Prostaglandin I2 (sodium salt)"
Prostaglandin I2 (PGI2) is an unstable cyclooxygenase metabolite detected first in vascular endothelial cells. It elevates platelet cAMP and is a potent vasodilator and inhibitor of human platelet aggregation with an IC50 of 5 nM. PGI2 is stable in basic buffers (pH=8), but it is rapidly hydrolyzed to 6-keto PGF1alpha in neutral or acidic solutions. The half-life is short both in vivo and in vitro, ranging from 30 seconds to a few minutes. PGI2 is administered by continuous infusion in humans for the treatment of idiopathic pulmonary hypertension. Formal Name: 6,9alpha-epoxy-11alpha,15S-dihydroxy-prosta-5Z,13E-dien-1-oic acid, monosodium salt. CAS Number: 61849-14-7. Synonyms: Epoprostenol, PGI2, Prostacyclin. Molecular Formula: C20H31O5 . Na. Formula Weight: 374.5. Purity: >98%. Formulation: A crystalline solid. Solubility: DMF: 5 mg/ml, DMSO: 5 mg/ml, Ethanol: 10 mg/ml*, PBS (pH >10.2): 10 mg/ml, Water: 10 mg/ml. SMILES: CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@H]2[C@@H]1C/C(O2)=C/CCCC([O-])=O.[Na+]. InChi Code: InChI=1S/C20H32O5.Na/c1-2-3-4-7-14(21)10-11-16-17-12-15(8-5-6-9-20(23)24)25-19(17)13-18(16)22,/h8,10-11,14,16-19,21-22H,2-7,9,12-13H2,1H3,(H,23,24),/q,+1/p-1/b11-10+,15-8-,/t14-,16+,17+,18+,19-,/m0./s1. InChi Key: LMHIPJMTZHDKEW-XQYLJSSYSA-M.
Keywords: Epoprostenol, PGI2, Prostacyclin, 6,9alpha-epoxy-11alpha,15S-dihydroxy-prosta-5Z,13E-dien-1-oic acid, monosodium salt
Supplier: Cayman Chemical
Supplier-Nr: 18220

Properties

Application: Bioactive lipid assays
MW: 374.5 D
Formula: C20H31O5 . Na
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 61849-14-7| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H302, H312, H332
P Phrases: P261, P264, P270, P271, P280, P301+310, P302+352, P304+340, P312, P321, P330, P361+364, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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