Prostaglandin F2alpha-1-glyceryl ester

Prostaglandin F2alpha-1-glyceryl ester
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10139-500 500 µg -

6 - 10 business days*

44.00€
Cay10139-1 1 mg -

6 - 10 business days*

75.00€
Cay10139-5 5 mg -

6 - 10 business days*

350.00€
 
2-Arachidonoyl glycerol (2-AG, Cay-62160) has been isolated from porcine brain, and has been... more
Product information "Prostaglandin F2alpha-1-glyceryl ester"
2-Arachidonoyl glycerol (2-AG, Cay-62160) has been isolated from porcine brain, and has been characterized as the natural endocannabinoid ligand for the central cannabinoid receptor. Incubation of 2-AG with cyclooxygenase-2 and specific prostaglandin H2 (PGH2) isomerases in cell cultures and isolated enzyme preparations results in PG glyceryl ester formation. The biosynthesis of PGH, PGD, PGE, PGF, and thromboxane A-2-glyceryl ester compounds have all been documented. The 2-glyceryl ester moiety equilibrates rapidly (within minutes) with the more stable 1-glyceryl ester, producing a 10:90 2:1-glyceryl ester mixture in typical aqueous media. While the stability and metabolism of PGF2alpha-1-glyceryl ester has been investigated, little is known about its intrinsic biological activity. Formal Name: 9alpha,11alpha,15S-trihydroxy-prosta-5Z,13E-dien-1-oic acid, 1-glyceryl ester. CAS Number: 43042-79-1. Synonyms: PGF2alpha-1-glyceryl ester. Molecular Formula: C23H40O7. Formula Weight: 428.6. Purity: >98% (as a 9:1 mixture of the 2- and 1-glyceryl esters). Formulation: A solution in ethanol. Solubility: DMF: 30 mg/ml, DMSO: 20 mg/ml, Ethanol: 30 mg/ml, PBS (pH 7.2): 500 µg/ml. SMILES: O[C@@H]1[C@H](C/C=C\CCCC(OCC(CO)O)=O)[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C1. InChi Code: InChI=1S/C23H40O7/c1-2-3-6-9-17(25)12-13-20-19(21(27)14-22(20)28)10-7-4-5-8-11-23(29)30-16-18(26)15-24/h4,7,12-13,17-22,24-28H,2-3,5-6,8-11,14-16H2,1H3/b7-4-,13-12+/t17-,18?,19+,20+,21-,22+/m0/s1. InChi Key: NWKPOVHSHWJQNI-OMVDPNNKSA-N.
Keywords: PGF2alpha-1-glyceryl ester, 9alpha,11alpha,15S-trihydroxy-prosta-5Z,13E-dien-1-oic acid, 1-glyceryl ester
Supplier: Cayman Chemical
Supplier-Nr: 10139

Properties

Application: Bioactive lipid assays
MW: 428.6 D
Formula: C23H40O7
Purity: >98% (as a 9:1 mixture of 2-& 1-glyceryl esters)
Format: Solution

Database Information

CAS : 43042-79-1| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225, H360
P Phrases: P201, P202, P210, P233, P240, P241, P242, P243, P280, P303+361+353, P308+313, P370+378, P403+235, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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