Prostaglandin E1

Prostaglandin E1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay13010-1 1 mg -

6 - 10 business days*

22.00€
Cay13010-5 5 mg -

6 - 10 business days*

90.00€
Cay13010-10 10 mg -

6 - 10 business days*

128.00€
Cay13010-50 50 mg -

6 - 10 business days*

585.00€
 
PGE1 is the theoretical cyclooxygenase metabolite of dihomo-gamma-linolenic acid (DGLA), but it... more
Product information "Prostaglandin E1"
PGE1 is the theoretical cyclooxygenase metabolite of dihomo-gamma-linolenic acid (DGLA), but it is virtually undetectable in the plasma of normal humans or other animals. Its pharmacology includes vasodilation, hypotension, and anti-platelet activities. The IC50 of PGE1 for the inhibition of ADP-induced human platelet aggregation is 40 nM. The vasorelaxant and anti-hypertensive effects of PGE1 are used to treat male erectile dysfunction and to provide emergency vasodilation of the patent ductus arteriosus in infants whose cardiac anomalies require pulmonary shunting for survival. In human males, the intracavernosal effective dose range for PGE1 is 2 to 80 µg, and the transurethral range is 125 to 1,000 µg. Formal Name: 9-oxo-11alpha,15S-dihydroxy-prost-13E-en-1-oic acid. CAS Number: 745-65-3. Synonyms: Alprostadil, PGE1. Molecular Formula: C20H34O5. Formula Weight: 354.5. Purity: >98%. Formulation: A crystalline solid. Solubility: DMF: 100 mg/ml, DMSO: 50 mg/ml, Ethanol: 50 mg/ml, PBS pH 7.2: 0.5 mg/ml. SMILES: O=C1[C@H](CCCCCCC(O)=O)[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C1. InChi Code: InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,19+/m0/s1. InChi Key: GMVPRGQOIOIIMI-DWKJAMRDSA-N.
Keywords: Alprostadil, PGE1, 9-oxo-11alpha,15S-dihydroxy-prost-13E-en-1-oic acid
Supplier: Cayman Chemical
Supplier-Nr: 13010

Properties

Application: Bioactive lipid assays
MW: 354.5 D
Formula: C20H34O5
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 745-65-3| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H302, H360
P Phrases: P201, P202, P264, P270, P280, P301+310, P308+313, P330, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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