Prostaglandin D2 Ethanolamide

Prostaglandin D2 Ethanolamide
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay12012-500 500 µg -

3 - 10 business days*

Cay12012-1 1 mg -

3 - 10 business days*

Cay12012-5 5 mg -

3 - 10 business days*

Prostaglandin D2 ethanolamide (PGD2-EA) is a bioactive lipid produced by the sequential... more
Product information "Prostaglandin D2 Ethanolamide"
Prostaglandin D2 ethanolamide (PGD2-EA) is a bioactive lipid produced by the sequential metabolism of anandamide (arachidonoyl ethanolamide) by cyclooxygenase (COX) enzymes, in particular by COX-2, and PGD synthase. The biosynthesis of PGD2-EA from anandamide can also be increased when anandamide metabolism is diminished by deletion of fatty acid amide hydrolase. PGD2-EA is inactive against recombinant prostanoid receptors, including the D prostanoid receptor. It increases the frequency of miniature inhibitory postsynaptic currents in primary cultured hippocampal neurons, an effect which is the opposite of that induced by anandamide.. PGD2-EA also induces apoptosis in colorectal carcinoma cell lines. Formal Name: N-(2-hydroxyethyl)-11-oxo-9alpha,15S-dihydroxy-prosta-5Z,13E-dien-1-amide. CAS Number: 398138-28-8. Synonyms: PGD2-EA, Prostamide D2. Molecular Formula: C22H37NO5. Formula Weight: 395.5. Purity: >96%. Formulation: A solution in ethanol. Solubility: DMF: 8.3 mg/ml, DMSO: 8.3 mg/ml, Ethanol: 12.5 mg/ml, PBS (7.2): 2.5 mg/ml. SMILES: CCCCCC(O)/C=C/[C@H]1C(=O)CC(O)C1C/C=C\CCCC(=O)NCCO. InChi Code: InChI=1S/C22H37NO5/c1-2-3-6-9-17(25)12-13-19-18(20(26)16-21(19)27)10-7-4-5-8-11-22(28)23-14-15-24/h4,7,12-13,17-20,24-26H,2-3,5-6,8-11,14-16H2,1H3,(H,23,28)/b7-4-,13-12+/t17-,18+,19+,20-/m0/s1. InChi Key: KEYDJKSQFDUAGF-YIRKRNQHSA-N.
Keywords: PGD2-EA, Prostamide D2, N-(2-hydroxyethyl)-11-oxo-9alpha,15S-dihydroxy-prosta-5Z,13E-dien-1-amide
Supplier: Cayman Chemical
Supplier-Nr: 12012


Application: Bioactive lipid assays
MW: 395.5 D
Formula: C22H37NO5
Purity: >96%
Format: Solution

Database Information

CAS : 398138-28-8| Find alternatives

Handling & Safety

Storage: -80°C
Shipping: -20°C (International: -80°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H302, H360
P Phrases: P201, P202, P264, P270, P280, P301+310, P308+313, P330, P405, P501
Our products are for laboratory research use only: Not for administration to humans!
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