Prostaglandin D2

Prostaglandin D2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay12010-1 1 mg -

3 - 10 business days*

49.00€
Cay12010-5 5 mg -

3 - 10 business days*

220.00€
Cay12010-10 10 mg -

3 - 10 business days*

367.00€
Cay12010-25 25 mg -

3 - 10 business days*

793.00€
 
Prostaglandin D2 (PGD2) is the major eicosanoid product of mast cells and is released in large... more
Product information "Prostaglandin D2"
Prostaglandin D2 (PGD2) is the major eicosanoid product of mast cells and is released in large quantities during allergic and asthmatic anaphylaxis. Mastocytosis patients produce excessive amounts of PGD2, which causes vasodilation, flushing, hypotension, and syncopal episodes. PGD2 is also produced in the brain via an alternative pathway involving a soluble, secreted PGD-synthase also known as beta-trace. In the brain, PGD2 produces normal physiological sleep and lowering of body temperature. Further pharmacological actions include inhibition of platelet aggregation and relaxation of vascular smooth muscle. PGD2 inhibits human ovarian tumor cell proliferation with an IC50 of 6.8 µM. Formal Name: 9alpha,15S-dihydroxy-11-oxo-prosta-5Z,13E-dien-1-oic acid. CAS Number: 41598-07-6. Synonyms: PGD2. Molecular Formula: C20H32O5. Formula Weight: 352.5. Purity: >98%. Formulation: A crystalline solid. Solubility: DMF: >100 mg/ml, DMSO: >50 mg/ml, Ethanol: >75 mg/ml, PBS pH 7.2: >5 mg/ml. SMILES: CCCCCC(O)/C=C/[C@H]1C(=O)CC(O)C1C/C=C\CCCC(=O)O. InChi Code: InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-18,21-22H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,18-/m0/s1. InChi Key: BHMBVRSPMRCCGG-OUTUXVNYSA-N.
Keywords: PGD2, 9alpha,15S-dihydroxy-11-oxo-prosta-5Z,13E-dien-1-oic acid
Supplier: Cayman Chemical
Supplier-Nr: 12010

Properties

Application: Bioactive lipid assays
MW: 352.5 D
Formula: C20H32O5
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 41598-07-6| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H302, H360
P Phrases: P201, P202, P264, P270, P280, P301+310, P308+313, P330, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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