PLC thio-PIP2 (sodium salt)

PLC thio-PIP2 (sodium salt)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10007839-100 100 µg -

6 - 10 business days*

115.00€
Cay10007839-500 500 µg -

6 - 10 business days*

518.00€
Cay10007839-1 1 mg -

6 - 10 business days*

920.00€
 
Phospholipase C (PLC) catalyzes the hydrolysis of phosphatidylinositol (4,5) bisphosphate (PIP2)... more
Product information "PLC thio-PIP2 (sodium salt)"
Phospholipase C (PLC) catalyzes the hydrolysis of phosphatidylinositol (4,5) bisphosphate (PIP2) on the cytoplasmic side of the cell membrane to yield diacylglycerol and inositol-1,4,5-triphosphate (IP3). This reaction initiates a well-known signal transduction pathway common to most cells. PLC thio-PIP2 is an analog of naturally occurring PIP2 that contains sulfur rather than oxygen at the sn-3 position of the glycerol backbone. Hydrolysis by PLC yields a free thiol which reacts with chromogenic reagents such as DTNB (Ellman's reagent) to allow quantitation of PLC activity. Formal Name: 3-(3-(1,2-dihydroxy-1,2-dihexanoyl)thiopropane)inositol-4,5-diphosphate, trisodium salt. Molecular Formula: C21H38O18P3S . 3Na. Formula Weight: 772.5. Purity: >98%. Formulation: A lyophilized powder. SMILES: CCCCCC(OC[C@@H](OC(CCCCC)=O)CSP([O-])(O[C@@H]1[C@H](O)[C@H](O)[C@@H](OP(O)([O-])=O)[C@H](OP(O)([O])=O)[C@H]1O)=O)=O.[Na+].[Na].[Na+]. InChi Code: InChI=1S/C21H41O18P3S.3Na/c1-3-5-7-9-14(22)35-11-13(36-15(23)10-8-6-4-2)12-43-42(33,34)39-19-16(24)17(25)20(37-40(27,28)29)21(18(19)26)38-41(30,31)32,,,/h13,16-21,24-26H,3-12H2,1-2H3,(H,33,34)(H2,27,28,29)(H2,30,31,32),,,/q,3*+1/p-3/t13-,16-,17+,18+,. InChi Key: JEAWYKPPKVXGTD-JORWXVKOSA-K.
Keywords: 3-(3-(1,2-dihydroxy-1,2-dihexanoyl)thiopropane)inositol-4,5-diphosphate, trisodium salt
Supplier: Cayman Chemical
Supplier-Nr: 10007839

Properties

Application: Bioactive lipid assays
MW: 772.5 D
Formula: C21H38O18P3S . 3Na
Purity: >98%
Format: Solid

Database Information

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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