Nepitrin

Nepitrin is a flavonoid glycoside that has been found in S. plebeia and has diverse biological activities. It protects lard from thermal oxidation when used at concentrations of 0.02 and 0.04%. Nepitrin inhibits carrageenin-induced edema and yeast-induced fever in rats. It decreases serum levels of triglycerides and LDL, as well as increases serum HDL levels, in a rat model of high-fat diet-induced atherosclerosis when administered at doses of 20 and 50 mg/kg.Formal Name: 2-(3,4-dihydroxyphenyl)-7-(beta-D-glucopyranosyloxy)-5-hydroxy-6-methoxy-4H-1-benzopyran-4-one. CAS Number: 569-90-4. Synonyms: 6-methoxy Luteolin-7-glucoside, Nepetin 7-O-glucoside. Molecular Formula: C22H22O12. Formula Weight: 478.4. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMSO: soluble. lambdamax: 258, 272, 350 nm. SMILES: OC1=C2C(OC(C3=CC(O)=C(C=C3)O)=CC2=O)=CC(O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO)=C1OC. InChi Code: InChI=1S/C22H22O12/c1-31-21-14(33-22-20(30)19(29)17(27)15(7-23)34-22)6-13-16(18(21)28)11(26)5-12(32-13)8-2-3-9(24)10(25)4-8/h2-6,15,17,19-20,22-25,27-30H,7H2,1H3/t15-,17-,19+,20-,22-/m1/s1. InChi Key: DMXHXBGUNHLMQO-IWLDQSELSA-N. Origin: Plant/Salvia plebeia.