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Product information "N,N-ditetradecylamine-pSar50-H"
N,N-ditetradecylamine-pSar50-H is an amine-functionalized hydrophilic polymer and a polysarcosine-conjugated form of ditetradecylamine. Polysarcosines (pSars) have been used as alternatives to PEGylated lipids in lipid nanoparticles (LNPs). Liposomes containing pSar exhibit similar physicochemical properties in vitro to those containing PEGylated lipids but do not undergo the accelerated blood clearance (ABC) phenomenon and show reduced immunogenicity in rats. For more information, please see Curapath's white paper: Polysarcosine (pSar) a safer, more effective alternative to poly-ethylene glycol (PEG).
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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