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Product information "N-3-oxo-dodecanoyl-L-Homoserine lactone"
N-3-oxo-dodecanoyl-L-Homoserine lactone (3-oxo-C12-HSL) is a bacterial quorum-sensing signaling molecule produced by P. aeruginosa and strains of the B. cepacia complex. It induces the production of IL-8 in 16HBE human bronchial epithelial cells when used at a concentration of 100 µM. Supernatants from 3-oxo-C12-HSL-stimulated 16HBE cells induce chemotaxis of isolated human neutrophils. 3-oxo-C12-HSL has been found in respiratory secretions from patients with cystic fibrosis infected with P. aeruginosa.Formal Name: 3-oxo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-dodecanamide. CAS Number: 168982-69-2. Synonyms: N-(3-oxododecanoyl) L-Homoserine lactone, 3-oxo-C12-HSL. Molecular Formula: C16H27NO4. Formula Weight: 297.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMSO: 20 mg/ml. lambdamax: 250 nm. SMILES: CCCCCCCCCC(=O)CC(=O)N[C@H]1CCOC1=O. InChi Code: InChI=1S/C16H27NO4/c1-2-3-4-5-6-7-8-9-13(18)12-15(19)17-14-10-11-21-16(14)20/h14H,2-12H2,1H3,(H,17,19)/t14-/m0/s1. InChi Key: PHSRRHGYXQCRPU-AWEZNQCLSA-N.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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