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Arachidonic acid is converted by microsomal CYP450 enzymes to a variety of epoxides, omega-1 and omega-hydroxylated compounds via what is known as the epoxidase pathway. MS-PPOH is a selective inhibitor of the epoxygenation reactions catalyzed by specific CYP450 isozymes. MS-PPOH inhibits the formation of arachidonate 11,12-epoxides by CYP4A2 and CYP4A3 enzymes with an IC50 value of 13 µM, but has no effect on the formation of 20-HETE, the omega-hydroxylation product of CYP4A1. Formal Name: N-(methylsulfonyl)-2-(2-propynyloxy)-benzenehexanamide. CAS Number: 206052-02-0. Molecular Formula: C16H21NO4S. Formula Weight: 323.4. Purity: >98%. Formulation: A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, DMSO:PBS (pH 7.2)(1:2): .30 mg/ml, Ethanol: 25 mg/ml. lambdamax: 218, 271 nm. SMILES: CCCOc1ccccc1CCCCCC(=O)NS(=O)(=O)C. InChi Code: InChI=1S/C16H21NO4S/c1-3-13-21-15-11-8-7-10-14(15)9-5-4-6-12-16(18)17-22(2,19)20/h1,7-8,10-11H,4-6,9,12-13H2,2H3,(H,17,18). InChi Key: REUHFEYPDFRRGJ-UHFFFAOYSA-N.