Montelukast (sodium salt)

Montelukast (sodium salt)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10008318-10 10 mg -

3 - 10 business days

18.00€
Cay10008318-50 50 mg -

3 - 10 business days

79.00€
Cay10008318-100 100 mg -

3 - 10 business days

140.00€
Cay10008318-500 500 mg -

3 - 10 business days

613.00€
 
The cysteinyl leukotrienes (CysLTs), LTC4 and LTD4, are potent mediators of asthma and... more
Product information "Montelukast (sodium salt)"
The cysteinyl leukotrienes (CysLTs), LTC4 and LTD4, are potent mediators of asthma and hypersensitivity. They induce bronchoconstriction, increase microvascular permeability, and are vasoconstrictors of coronary arteries. Their biological effects are transduced by a pair of G protein-coupled receptors, CysLT1 and CysLT2. Montelukast (sodium salt) is a potent, selective cysteinyl leukotriene 1 (CysLT1) receptor antagonist sold under the trade name Singulair for the treatment of asthma as well as for the symptoms associated with allergic rhinitis. It binds to the human CysLT1 receptor with an IC50 of less than 5 nM with no appreciable binding to the CysLT2 receptor.
Keywords: MK-476, 1-[[[(1R)-1-[3-(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]-methyl]-cyclopropaneacetic acid, monosodium salt
Supplier: Cayman Chemical
Supplier-Nr: 10008318-10

Properties

Application: CysLT1 receptor antagonist
MW: 608.2 D
Formula: C35H35ClNO3S . Na
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 151767-02-1| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H318
P Phrases: P280, P310, P305+P351+P338
Caution
Our products are for laboratory research use only: Not for administration to humans!
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