Methyl Arachidonyl Fluorophosphonate

Methyl Arachidonyl Fluorophosphonate
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay70660-1 1 mg -

6 - 10 business days*

Cay70660-5 5 mg -

6 - 10 business days*

Cay70660-10 10 mg -

6 - 10 business days*

Cay70660-25 25 mg -

6 - 10 business days*

Methyl arachidonyl fluorophosphonate (MAFP) is an inhibitor of monoacylglycerol lipase (MAGL) and... more
Product information "Methyl Arachidonyl Fluorophosphonate"
Methyl arachidonyl fluorophosphonate (MAFP) is an inhibitor of monoacylglycerol lipase (MAGL) and fatty acid amide hydrolase (FAAH, IC50s = 26 and 0.33 nM, respectively). It is also an irreversible inhibitor of cytosolic phospholipase A2 (cPLA2), as well as calcium-independent PLA2 (iPLA2, IC50 = 500 nM). MAFP inhibits A23187-induced arachidonic acid release from human platelets with an IC50 value of 600 nM. Formal Name: 5Z,8Z,11Z,14Z-eicosatetraenyl-phosphonofluoridic acid, methyl ester. CAS Number: 188404-10-6. Synonyms: MAFP. Molecular Formula: C21H36FO2P. Formula Weight: 370.5. Purity: >98%. Formulation: A solution in methyl acetate. Solubility: DMF: 3 mg/ml, DMSO: 3 mg/ml, Ethanol: 3.5 mg/ml, Ethanol:PBS (pH 7.2) 1:1: .5 mg/ml, PBS (7.2): <1 mg/ml (colloidal suspension. SMILES: CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCCP(F)(OC)=O. InChi Code: InChI=1S/C21H36FO2P/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-25(22,23)24-2/h7-8,10-11,13-14,16-17H,3-6,9,12,15,18-21H2,1-2H3/b8-7-,11-10-,14-13-,17-16-. InChi Key: KWKZCGMJGHHOKJ-ZKWNWVNESA-N.
Keywords: MAFP, 5Z,8Z,11Z,14Z-eicosatetraenyl-phosphonofluoridic acid, methyl ester
Supplier: Cayman Chemical
Supplier-Nr: 70660


Application: PLA2 inhibitor
MW: 370.5 D
Formula: C21H36FO2P
Purity: >98%
Format: Solution

Database Information

CAS : 188404-10-6| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: EUH066, H225, H319, H336
P Phrases: , P210, P233, P240, P241, P242, P243, P261, P264, P271, P280, P303+361+353, P304+340, P305+351+338, P312, P337+313, P370+378, P403+233, P403+235, P405, P501
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