m-Coumaric Acid

m-Coumaric acid is an active metabolite of various polyphenols, including chlorogenic acid (Cay-70930) and rosmarinic acid (Cay-70900). It inhibits cumene hydroperoxide-induced oxidation of DNA (IC50 = 54.7 µM). m-Coumaric acid (10 µM) induces neurite outgrowth of fetal rat hippocampal neurons. It induces apoptosis and cell cycle arrest at the G0/G1 phase in HeLa cervical cancer cells when used at concentrations of 5 and 10 mM, respectively. m-Coumaric acid (3 mmol/kg) increases locomotor activity in mice.Formal Name: 3-(3-hydroxyphenyl)-2-propenoic acid. CAS Number: 588-30-7. Synonyms: 3-hydroxy Cinnamic Acid, m-hydroxy Cinnamic Acid, meta-hydroxy Cinnamic Acid, 3-Coumaric Acid, meta-Coumaric Acid, NSC 28956, NSC 50308. Molecular Formula: C9H8O3. Formula Weight: 164.2. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: Soluble, Methanol: Soluble. lambdamax: 215, 234, 279 nm. SMILES: O=C(C=CC1=CC(O)=CC=C1)O. InChi Code: InChI=1S/C9H8O3/c10-8-3-1-2-7(6-8)4-5-9(11)12/h1-6,10H,(H,11,12). InChi Key: KKSDGJDHHZEWEP-UHFFFAOYSA-N. Origin: Synthetic.