Lysophosphatidylethanolamine (egg)

Lysophosphatidylethanolamine (LPE) is a naturally-occurring lysophospholipid that can be generated via deacylation of phosphatidylethanolamine by phospholipase A2 (PLA2). It increases the phosphorylation of ERK1/2 in PC12 cells, an effect that can be blocked by the MEK inhibitors U-0126 (Cay-70970) and PD 98059 (Cay-10006726) and the EGFR inhibitor AG-1478 (Cay-10010244). LPE also increases neurite outgrowth and expression of neurofilament M in PC12 cells. LPE inhibits the activity of phospholipase D (PLD) partially purified from cabbage. This product contains lysophosphatidylethanolamine molecular species with variable fatty acyl chain lengths at the sn-1 position and a hydroxy group at the sn-2 position.CAS Number: 97281-40-8. Synonyms: Lyso-PE (egg), LPE (egg), L-alpha-lysophosphatidylethanolamine. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: Chloroform: Soluble. SMILES: O[C@@H](COP(OCC[NH3+])([O-])=O)COC([R])=O.