LY171883

LY171883
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay70710-5 5 mg -

6 - 10 business days*

40.00€
Cay70710-10 10 mg -

6 - 10 business days*

77.00€
Cay70710-50 50 mg -

6 - 10 business days*

320.00€
Cay70710-100 100 mg -

6 - 10 business days*

560.00€
 
LY171883 is a selective, potent, orally active antagonist of the leukotriene D4 receptor.... more
Product information "LY171883"
LY171883 is a selective, potent, orally active antagonist of the leukotriene D4 receptor. Dissociation constants (KB) for LY171883 on guinea pig ileum and parenchyma are 0.07 and 0.34 µM, respectively. LY171883 is an inhibitor of phosphodiesterase obtained from human polymorphonuclear leukocytes (IC50 of 22.6 µM) and various guinea pig tissues (IC50s range from 6.9-209 µM). At a concentration of 50-100 µM, LY171883 binds to the PPARgamma nuclear receptor, inducing adipogenesis in cultured NIH3T3 fibroblasts. Formal Name: 1-[2-hydroxy-3-propyl-4-[4-(1H-tetrazol-5-yl)butoxy]phenyl]-ethanone. CAS Number: 88107-10-2. Molecular Formula: C16H22N4O3. Formula Weight: 318.4. Purity: >98%. Formulation: A crystalline solid. Solubility: DMF: 25 mg/ml, DMSO: 25 mg/ml, Ethanol: 25 mg/ml, Sodium Bicarbonate (0.5M): 15 mg/ml. lambdamax: 218, 284 nm. SMILES: CCCc1c(OCCCCc2nnn[nH]2)ccc(C(=O)C)c1O. InChi Code: InChI=1S/C16H22N4O3/c1-3-6-13-14(9-8-12(11(2)21)16(13)22)23-10-5-4-7-15-17-19-20-18-15/h8-9,22H,3-7,10H2,1-2H3,(H,17,18,19,20). InChi Key: MWYHLEQJTQJHSS-UHFFFAOYSA-N.
Keywords: 1-[2-hydroxy-3-propyl-4-[4-(1H-tetrazol-5-yl)butoxy]phenyl]-ethanone
Supplier: Cayman Chemical
Supplier-Nr: 70710

Properties

Application: CysLTR1 antagonist
MW: 318.4 D
Formula: C16H22N4O3
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 88107-10-2| Find alternatives
KEGG ID : K04322 | Find alternatives

Handling & Safety

Storage: +20°C
Shipping: +20°C (International: +20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H302
P Phrases: P264, P270, P301+310, P330, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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