Limaprost

Limaprost
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay13810-1 1 mg -

6 - 10 business days*

82.00€
Cay13810-5 5 mg -

6 - 10 business days*

367.00€
Cay13810-10 10 mg -

6 - 10 business days*

610.00€
 
Limaprost is an analog of PGE1 with structural modifications intended to give it a prolonged... more
Product information "Limaprost"
Limaprost is an analog of PGE1 with structural modifications intended to give it a prolonged half-life and greater potency. Limaprost is orally active in both rats and guinea pigs at doses of 100 µg/kg as an inhibitor of ADP and collagen induced platelet aggregation. Limaprost is 10-1,000 times more potent than PGE1 as an inhibitor of platelet adhesiveness measured in vitro. Intra-coronary injection (100 ng/kg) or intravenous injection (3 µg/kg) in anesthetized dogs causes vasodilation and increased coronary blood flow by 60-80%. Significant hypotensive effects were seen at 100 and 300 µg/kg orally in rats. Formal Name: 11alpha,15S-dihydroxy-17S,20-dimethyl-9-oxo-prosta-2E,13E-dien-1-oic acid. CAS Number: 74397-12-9. Synonyms: 17alpha,20-dimethyl-Delta2-PGE1, 17alpha,20-dimethyl-Delta2-Prostaglandin E1. Molecular Formula: C22H36O5. Formula Weight: 380.5. Purity: >98%. Formulation: A crystalline solid. Solubility: DMF: >30 mg/ml, DMSO: >130 mg/ml, Ethanol: >50 mg/ml, PBS pH 7.2: >2 mg/ml. SMILES: O[C@H]1[C@H](/C=C/[C@@H](O)C[C@@H](C)CCCC)[C@@H](CCCC/C=C/C(O)=O)C(C1)=O. InChi Code: InChI=1S/C22H36O5/c1-3-4-9-16(2)14-17(23)12-13-19-18(20(24)15-21(19)25)10-7-5-6-8-11-22(26)27/h8,11-13,16-19,21,23,25H,3-7,9-10,14-15H2,1-2H3,(H,26,27)/b11-8+,13-12+/t16-,17+,18+,19+,21+/m0/s1. InChi Key: OJZYRQPMEIEQFC-UAWLTFRCSA-N.
Keywords: 17alpha,20-dimethyl-Delta2-PGE1, 17alpha,20-dimethyl-Delta2-Prostaglandin E1, 11alpha,15S-dihydroxy-17S,20-dimethyl-9-oxo-prosta-2E,13E-dien-1-oic acid
Supplier: Cayman Chemical
Supplier-Nr: 13810

Properties

Application: PGE1 analog
MW: 380.5 D
Formula: C22H36O5
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 74397-12-9| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H300
P Phrases: P264, P270, P301+310, P321, P330, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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