Leukotriene E4-d5

Leukotriene E4-d5
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10007858-25 25 µg -

6 - 10 business days*

282.00€
Cay10007858-50 50 µg -

6 - 10 business days*

479.00€
Cay10007858-100 100 µg -

6 - 10 business days*

900.00€
 
Leukotriene E4-d5 (LTE4-d5) contains five deuterium atoms at the 19, 19', 20, 20 and 20... more
Product information "Leukotriene E4-d5"
Leukotriene E4-d5 (LTE4-d5) contains five deuterium atoms at the 19, 19', 20, 20 and 20 positions. It is intended for use as an internal standard for the quantification of LTE4 by GC- or LC-mass spectrometry. LTE4 is produced by the action of dipeptidase on LTD4, leaving only the cysteinyl group still attached to the fatty acid backbone. It is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A). LTE4 is considerably less active (8 to 12-fold) than LTC4 in the biological activities characteristic of cysteinyl leukotrienes. Unlike LTC4 and LTD4, LTE4 accumulates in both plasma and urine. Therefore, urinary excretion of LTE4 is most often used as an indicator of asthma. In humans, basal levels of LTE4 range from 1-100 pg/mg creatinine. In asthmatic patients, urinary LTE4 levels increase to 80-1,000 pg/mg creatinine. Formal Name: 5S-hydroxy-6R-(S-cysteinyl)-7E,9E,11Z,14Z-eicosatetraenoic-19,19,20,20,20-d5 acid. CAS Number: 1240398-14-4. Synonyms: LTE4-d5. Molecular Formula: C23H32D5NO5S. Formula Weight: 444.6. Purity: >99% deuterated forms (d1-d5). Formulation: A solution in ethanol. Solubility: DMF: >50 mg/ml, DMSO: >50 mg/ml, Ethanol: >50 mg/ml, PBS (pH 7.2): >100 µg/ml. lambdamax: 281 nm. SMILES: O[C@H](CCCC(O)=O)[C@H](SC[C@H](N)C(O)=O)/C=C/C=C/C=C\C/C=C\CCCC([2H])([2H])C([2H])([2H])[2H]. InChi Code: InChI=1S/C23H37NO5S/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-21(30-18-19(24)23(28)29)20(25)15-14-17-22(26)27/h6-7,9-13,16,19-21,25H,2-5,8,14-15,17-18,24H2,1H3,(H,26,27)(H,28,29)/b7-6-,10-9-,12-11+,16-13+/t19?,20-,21+/m0/s1/i1D3,2D2. InChi Key: OTZRAYGBFWZKMX-QDHCSUQMSA-N.
Keywords: LTE4-d5, 5S-hydroxy-6R-(S-cysteinyl)-7E,9E,11Z,14Z-eicosatetraenoic-19,19,20,20,20-d5 acid
Supplier: Cayman Chemical
Supplier-Nr: 10007858

Properties

Application: Standard
MW: 444.6 D
Formula: C23H32D5NO5S
Purity: >99% deuterated forms (d1-d5)
Format: Solution

Database Information

CAS : 1240398-14-4| Find alternatives

Handling & Safety

Storage: -80°C
Shipping: -20°C (International: -80°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225
P Phrases: P210, P233, P240, P241, P242, P243, P280, P303+361+353, P370+378, P403+235, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow. more
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Leukotriene E4-d5"
Write a review
or to review a product.
Viewed