Leukotriene C4-d5

Leukotriene C4-d5
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10006198-25 25 µg -

3 - 10 business days*

287.00€
Cay10006198-50 50 µg -

3 - 10 business days*

544.00€
Cay10006198-100 100 µg -

3 - 10 business days*

1,030.00€
 
Leukotriene C4-d5 (LTC4-d5) contains five deuterium atoms at the 19, 19', 20, 20 and 20... more
Product information "Leukotriene C4-d5"
Leukotriene C4-d5 (LTC4-d5) contains five deuterium atoms at the 19, 19', 20, 20 and 20 positions. It is intended for use as an internal standard for the quantification of LTC4 by GC- or LC-mass spectrometry. LTC4 is the parent cysteinyl leukotriene produced by the LTC4 synthase catalyzed conjugation of glutathione to LTA4. LTC4 is produced by neutrophils, macrophages, and mast cells, and by transcellular metabolism in platelets. It is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A) and exhibits potent smooth muscle contracting activity. LTC4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute allergic hypersensitivity. The concentration of LTC4 required to produce marked contractions of lung parenchymal strips and isolated tracheal rings is about 1 nM. Formal Name: 5S-hydroxy-6R-(S-glutathionyl)-7E,9E,11Z,14Z-d5-eicosatetraenoic acid. CAS Number: 1441421-73-3. Synonyms: LTC4-d5. Molecular Formula: C30H42D5N3O9S. Formula Weight: 630.8. Purity: >99% deuterated forms (d1-d5). Formulation: A solution in ethanol:water (95:5). Solubility: DMF: 50 mg/ml, DMSO: 50 mg/ml, Ethanol: 1 mg/ml, Ethanol:H20 (95:5): 2 mg/ml, PBS (pH 7.2): 0.1 mg/ml. lambdamax: 280 nm. SMILES: O[C@@H](CCCC(O)=O)[C@H](SC[C@H](NC(CC[C@H](N)C(O)=O)=O)C(NCC(O)=O)=O)/C=C/C=C/C=C\C/C=C\CCCC([2H])([2H])C([2H])([2H])[2H]. InChi Code: InChI=1S/C30H47N3O9S/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-25(24(34)15-14-17-27(36)37)43-21-23(29(40)32-20-28(38)39)33-26(35)19-18-22(31)30(41)42/h6-7,9-13,16,22-25,34H,2-5,8,14-15,17-21,31H2,1H3,(H,32,40)(H,33,35)(H,36,37)(H,38,39)(H,41,42)/b7-6-,10-9-,. InChi Key: GWNVDXQDILPJIG-PTOIOBJSSA-N.
Keywords: LTC4-d5, 5S-hydroxy-6R-(S-glutathionyl)-7E,9E,11Z,14Z-d5-eicosatetraenoic acid
Supplier: Cayman Chemical
Supplier-Nr: 10006198

Properties

Application: Standard
MW: 630.8 D
Formula: C30H42D5N3O9S
Purity: >99% deuterated forms (d1-d5)
Format: Solution

Database Information

CAS : 1441421-73-3| Find alternatives
KEGG ID : K00807 | Find alternatives

Handling & Safety

Storage: -80°C
Shipping: -20°C (International: -80°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225
P Phrases: P210, P233, P240, P241, P242, P243, P280, P303+361+353, P370+378, P403+235, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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