Fludrocortisone Acetate

Fludrocortisone acetate is the acetate form of the synthetic corticosteroid fludrocortisone, which is a mineralocorticoid receptor agonist. Fludrocortisone acetate (0.1-5 µg/animal) promotes sodium retention in rats in a dose-dependent manner with 37% of sodium excreted compared with control when used at a dose of 5 µg/animal. Formulations containing fludrocortisone acetate have been used in the treatment of Addison's disease.Formal Name: 21-(acetyloxy)-9-fluoro-11beta,17-dihydroxy-pregn-4-ene-3,20-dione. CAS Number: 514-36-3. Synonyms: 9alpha-fluoro Hydrocortisone Acetate, NSC 15186, U 4845. Molecular Formula: C23H31FO6. Formula Weight: 422.5. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: Chloroform: Slightly Soluble, Methanol: Slightly Soluble. lambdamax: 239 nm. SMILES: F[C@]12[C@@]([C@@](CC[C@]3(O)C(COC(C)=O)=O)([H])[C@]3(C)C[C@@H]2O)([H])CCC4=CC(CC[C@@]41C)=O. InChi Code: InChI=1S/C23H31FO6/c1-13(25)30-12-19(28)22(29)9-7-16-17-5-4-14-10-15(26)6-8-20(14,2)23(17,24)18(27)11-21(16,22)3/h10,16-18,27,29H,4-9,11-12H2,1-3H3/t16-,17-,18-,20-,21-,22-,23-/m0/s1. InChi Key: SYWHXTATXSMDSB-GSLJADNHSA-N.