Estriol-d2

Estriol-d2 is intended for use as an internal standard for the quantification of estriol (Cay-10006484) by GC- or LC-MS. Estriol is a metabolite of estradiol (Cay-ISO60155, Cay-10006315) and a major estrogen produced in the later stages of pregnancy. In a longitudinal study in healthy pregnant women, total plasma estriol levels increased from 15873) and serves as a direct marker of fetal adrenal gland activity. Saliva contains primarily unbound and unconjugated estriol and is commonly used for monitoring estriol levels. Plasma levels of estriol in males and non-pregnant females is less than 2 ng/ml.Formal Name: estra-1,3,5(10)-triene-2,4-d2-3,16alpha,17beta-triol. CAS Number: 53866-32-3. Synonyms: E3-d2, 16alpha-hydroxy-17beta-Estradiol-d2, 1,3,5(10)-Estratriene-3,16alpha,17beta-triol-d2. Molecular Formula: C18H22D2O3. Formula Weight: 290.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMF:PBS (pH 7.2) (1:1): 0.5 mg/ml, DMSO: 20 mg/ml, Ethanol: 5 mg/ml. lambdamax: 281 nm. SMILES: OC1=C([2H])C=C2C(CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])C[C@@H](O)[C@@H]4O)=C1[2H]. InChi Code: InChI=1S/C18H24O3/c1-18-7-6-13-12-5-3-11(19)8-10(12)2-4-14(13)15(18)9-16(20)17(18)21/h3,5,8,13-17,19-21H,2,4,6-7,9H2,1H3/t13-,14-,15+,16-,17+,18+/m1/s1/i3D,8D. InChi Key: PROQIPRRNZUXQM-JOFMCETISA-N.