Estriol

Estriol is a metabolite of estradiol and a major estrogen produced in the later stages of pregnancy. In a longitudinal study in healthy pregnant women, total plasma estriol levels increased from 10 weeks gestation to approximately 150 ng/ml at week 38. The majority of the estriol synthesized in the later stages of pregnancy originates from fetal dehydroepiandrosterone sulfate (DHEAS) and serves as a direct marker of fetal adrenal gland activity. Saliva contains primarily unbound and unconjugated estriol and is commonly used for monitoring estriol levels. Plasma levels of estriol in males and non-pregnant females is less than 2 ng/ml.Formal Name: estra-1,3,5(10)-triene-3,16alpha,17beta-triol. CAS Number: 50-27-1. Synonyms: E3, 16alpha-hydroxy-17beta-Estradiol, 1,3,5(10)-Estratriene-3,16alpha,17beta-triol. Molecular Formula: C18H24O3. Formula Weight: 288.4. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml, DMSO: 20 mg/ml, Ethanol: 5 mg/ml. lambdamax: 281 nm. SMILES: Oc1ccc2c(CC[C@@H]3C2CC[C@]2(C)[C@@H](O)C(O)CC32)c1. InChi Code: InChI=1S/C18H24O3/c1-18-7-6-13-12-5-3-11(19)8-10(12)2-4-14(13)15(18)9-16(20)17(18)21/h3,5,8,13-17,19-21H,2,4,6-7,9H2,1H3/t13-,14-,15+,16-,17+,18+/m1/s1. InChi Key: PROQIPRRNZUXQM-ZXXIGWHRSA-N.