Ergosterol Peroxide

Ergosterol Peroxide
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay30860-500 500 µg -

6 - 10 business days*

111.00€
Cay30860-1 1 mg -

6 - 10 business days*

208.00€
Cay30860-5 5 mg -

6 - 10 business days*

812.00€
 
Ergosterol peroxide is an oxidized sterol and derivative of ergosterol (Cay-19850) that has been... more
Product information "Ergosterol Peroxide"
Ergosterol peroxide is an oxidized sterol and derivative of ergosterol (Cay-19850) that has been found in S. aspratus and has diverse biological activities. It is active against the P. falciparum chloroquine-sensitive strain FCA 20/GHA with an IC50 value of 8.2 µM. Ergosterol peroxide (6.25-50 µM) induces apoptosis in LNCaP and DU145 prostate cancer cells. It inhibits growth of SNU-1 gastric, SNU-354 hepatoma, and SNU-C4 colorectal cancer cells (IC50s = 18.7, 158.2, and 84.6 µM, respectively). Ergosterol peroxide (60 µM) inhibits LPS-induced NF-kB DNA-binding activity and production of TNF-alpha in RAW 264.7 cells. Topical application of ergosterol peroxide reduces ear edema in a mouse model of inflammation induced by phorbol 12-myristate 13-acetate (TPA, Cay-10008014) with an ID50 value of 0.2 mg/ear.Formal Name: (3beta,5alpha,8alpha,22E)-5,8-epidioxy-ergosta-6,22-dien-3-ol. CAS Number: 2061-64-5. Synonyms: Ergosterol Endoperoxide, NSC 31324. Molecular Formula: C28H44O3. Formula Weight: 428.7. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: Methanol: soluble. SMILES: CC(C)[C@@H](C)/C=C/[C@@H](C)[C@@]1([H])CC[C@@]2([H])[C@@]3(OO4)C=C[C@@]54C[C@@H](O)CC[C@]5(C)[C@@]3([H])CC[C@@]21C. InChi Code: InChI=1S/C28H44O3/c1-18(2)19(3)7-8-20(4)22-9-10-23-25(22,5)13-12-24-26(6)14-11-21(29)17-27(26)15-16-28(23,24)31-30-27/h7-8,15-16,18-24,29H,9-14,17H2,1-6H3/b8-7+/t19-,20+,21-,22+,23+,24+,25+,26+,27+,28-/m0/s1. InChi Key: VXOZCESVZIRHCJ-KGHQQZOUSA-N. Origin: Plant/Unidentified sp..
Keywords: Ergosterol Endoperoxide, NSC 31324, (3beta,5alpha,8alpha,22E)-5,8-epidioxy-ergosta-6,22-dien-3-ol
Supplier: Cayman Chemical
Supplier-Nr: 30860

Properties

Application: Bioactive oxidized sterol
MW: 428.7 D
Formula: C28H44O3
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 2061-64-5| Matching products

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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