ent-Prostaglandin E2

ent-Prostaglandin E2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10008294-100 100 µg -

6 - 10 business days*

44.00€
Cay10008294-500 500 µg -

6 - 10 business days*

79.00€
Cay10008294-1 1 mg -

6 - 10 business days*

373.00€
 
Enzymatically-derived PGE2 is an optically pure compound whereas PGE2 derived from the free... more
Product information "ent-Prostaglandin E2"
Enzymatically-derived PGE2 is an optically pure compound whereas PGE2 derived from the free radical-catalyzed peroxidation of arachidonate is a racemic mixture. Ent-PGE2 is the opposite enantiomer of PGE2. Significant amounts of racemic PGE2 (rac-PGE2) are generated in vitro and in vivo in settings of oxidative stress via the isoprostane pathway. A proposed mechanism for the formation of rac-PGE2 involves the base catalyzed equilibration from 15-E2t-isoprostane (8-iso-PGE2), generated from the 15-H2t-isoprostane endoperoxide. Formal Name: 9-oxo-11beta,15R-dihydroxy-(8beta,12alpha)-prosta-5Z,13E-dien-1-oic acid. CAS Number: 65085-69-0. Synonyms: ent-PGE2. Molecular Formula: C20H32O5. Formula Weight: 352.5. Purity: >98%. Formulation: A solution in methyl acetate. Solubility: DMF: 50 mg/ml, DMSO: 50 mg/ml, Ethanol: 50 mg/ml, PBS (pH 7.2): 2 mg/ml. SMILES: O=C1[C@@H](C/C=C\CCCC(O)=O)[C@H](/C=C/[C@H](O)CCCCC)[C@@H](O)C1. InChi Code: InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,19+/m1/s1. InChi Key: XEYBRNLFEZDVAW-OBUVHCMGSA-N.
Keywords: ent-PGE2, 9-oxo-11beta,15R-dihydroxy-(8beta,12alpha)-prosta-5Z,13E-dien-1-oic acid
Supplier: Cayman Chemical
Supplier-Nr: 10008294

Properties

Application: Bioactive lipid assays
MW: 352.5 D
Formula: C20H32O5
Purity: >98%
Format: Solution

Database Information

CAS : 65085-69-0| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: EUH066, H225, H319, H336, H360
P Phrases: , P201, P202, P210, P233, P240, P241, P242, P243, P261, P264, P271, P280, P303+361+353, P304+340, P305+351+338, P308+313, P312, P337+313, P370+378, P403+233, P403+235, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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