ent-8-iso-15(S)-Prostaglandin F2alpha

ent-8-iso-15(S)-Prostaglandin F2alpha
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10010380-25 25 µg -

6 - 10 business days*

123.00€
Cay10010380-50 50 µg -

6 - 10 business days*

233.00€
Cay10010380-100 100 µg -

6 - 10 business days*

442.00€
 
Isoprostanes are produced by the non-enzymatic, free radical peroxidation of... more
Product information "ent-8-iso-15(S)-Prostaglandin F2alpha"
Isoprostanes are produced by the non-enzymatic, free radical peroxidation of phospholipid-esterified arachidonic acid. They have been used as biomarkers of oxidative stress, but they also have been found to have potent biological activity. ent-8-iso-15(S)-Prostaglandin F2alpha (ent-8-iso-15(S)-PGF2alpha) is a potent vasoconstrictor of porcine retinal and brain microvessels with EC50 values of 15 and 24 nM, respectively. This isoprostane is about ten-fold more potent than 8-iso-PGF2alpha in a whole blood platelet aggregation inhibition assay. Formal Name: 9beta,11beta,15S-trihydroxy-(12beta)-prosta-5Z,13E-dien-1-oic acid. CAS Number: 214748-66-0. Synonyms: ent-15-epi-F2t-Isoprostane, ent-8-iso-15-epi-PGF2alpha. Molecular Formula: C20H34O5. Formula Weight: 354.5. Purity: >98%. Formulation: A solution in acetonitrile. Solubility: 10 mM Na2CO3: >6.5 mg/ml, DMF: >100 mg/ml, DMSO: >100 mg/ml, Ethanol: >100 mg/ml, PBS (pH 7.2): >10 mg/ml. SMILES: O[C@H]1[C@H](C/C=C\CCCC(O)=O)[C@H](/C=C/[C@@H](O)CCCCC)[C@@H](O)C1. InChi Code: InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-19,21-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17-,18+,19-/m0/s1. InChi Key: PXGPLTODNUVGFL-XNTKLVSTSA-N.
Keywords: ent-15-epi-F2t-Isoprostane, ent-8-iso-15-epi-PGF2alpha, 9beta,11beta,15S-trihydroxy-(12beta)-prosta-5Z,13E-dien-1-oic acid
Supplier: Cayman Chemical
Supplier-Nr: 10010380

Properties

Application: Bioactive lipid assays
MW: 354.5 D
Formula: C20H34O5
Purity: >98%
Format: Solution

Database Information

CAS : 214748-66-0| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225, H302+312+332, H319, H360
P Phrases: , P201, P202, P210, P233, P240, P241, P242, P243, P264, P280, P303+361+353, P305+351+338, P308+313, P337+313, P370+378, P403+235, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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